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Aluminum+oxide-Silicon+oxide
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Aluminum+oxide-Silicon+oxide
Artikel-Nr:
(BOSSBS-11987R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11987R-CY7
Lokale Artikelnummer::
BOSSBS-11987R-CY7
Beschreibung:
CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12565R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12565R
Lokale Artikelnummer::
BOSSBS-12565R
Beschreibung:
ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13394R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13394R-CY5
Lokale Artikelnummer::
BOSSBS-13394R-CY5
Beschreibung:
Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13394R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13394R-HRP
Lokale Artikelnummer::
BOSSBS-13394R-HRP
Beschreibung:
Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2072R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2072R-CY5
Lokale Artikelnummer::
BOSSBS-2072R-CY5
Beschreibung:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a 45 kDa protein, which is identified as isocitrate dehydrogenase (IDH1). It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, formingalpha-ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production ofalpha-ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.
Artikel-Nr:
(BOSSBS-12461R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12461R
Lokale Artikelnummer::
BOSSBS-12461R
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12461R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12461R-A680
Lokale Artikelnummer::
BOSSBS-12461R-A680
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyses the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2072R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2072R-A555
Lokale Artikelnummer::
BOSSBS-2072R-A555
Beschreibung:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13387R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13387R-CY7
Lokale Artikelnummer::
BOSSBS-13387R-CY7
Beschreibung:
Glucose Oxidase is a dimeric enzyme that binds to β-D-glucose and aids in its oxidation into D-glucono-1,5-lactone which then hydrolyzes to gluconic acid. Flavin adenine dinucleotide (FAD) is a cofactor to Glucose Oxidase that acts as the initial electron acceptor and is required for this oxidation to occur. Glucose Oxidase is a natural preservative found in honey, where it reduces atmospheric oxygen into hydrogen peroxide which acts as an antibacterial barrier. Glucose Oxidase is also commonly used in biosensors in which it conveys levels of glucose by keeping track of the number of electrons passed through the enzyme. In this application, Glucose Oxidase is connected to an electrode and the resulting charge is measured.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD491669-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD491669-1G
Lokale Artikelnummer::
BLDPBD491669-1G
Beschreibung:
(S)-3,3'-Bis(3,5-di-tert-butylphenyl)-1,1'-binapthyl-2,2'-diyl hydrogenphosphate 98%
VE:
1 * 1 g
Artikel-Nr:
(BSENC-1542-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
C-1542-100
Lokale Artikelnummer::
BSENC-1542-100
Beschreibung:
Uncoupling Protein 3 (UCP3) belongs to the mitochondrial carrier family. Located in the mitochondrion inner membrane, UCP3 creates proton leaks across the membrane thus uncoupling oxidative phosphorylation (Ref: SWISSPROT).
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-171-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-171-100
Lokale Artikelnummer::
BSENR-171-100
Beschreibung:
GPx-P belongs to the glutathione peroxidase family which are responsible for the detoxification of hydrogen peroxide. It protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. GPx-P is secreted in plasma and exists as a homotetramer.
VE:
1 * 100 µl
Artikel-Nr:
(USBIE3010-86E-BIOT)
Lieferant:
US Biological
Hersteller-Artikelnummer::
E3010-86E-BIOT
Lokale Artikelnummer::
USBIE3010-86E-BIOT
Beschreibung:
Anti-NOS3 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-4157R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4157R-CY3
Lokale Artikelnummer::
BOSSBS-4157R-CY3
Beschreibung:
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3883R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3883R-CY3
Lokale Artikelnummer::
BOSSBS-3883R-CY3
Beschreibung:
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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