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2-Amino-6-brompyridin
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2-Amino-6-brompyridin
Artikel-Nr:
(BOSSBS-3410R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3410R-FITC
Lokale Artikelnummer::
BOSSBS-3410R-FITC
Beschreibung:
Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3412R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3412R-A680
Lokale Artikelnummer::
BOSSBS-3412R-A680
Beschreibung:
Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3410R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3410R-A680
Lokale Artikelnummer::
BOSSBS-3410R-A680
Beschreibung:
Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6592R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6592R
Lokale Artikelnummer::
BOSSBS-6592R
Beschreibung:
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.Tissue specificity; Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.Sequence similarities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13544R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13544R-A680
Lokale Artikelnummer::
BOSSBS-13544R-A680
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13544R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13544R-CY3
Lokale Artikelnummer::
BOSSBS-13544R-CY3
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
VE:
1 * 100 µl
Artikel-Nr:
(40075.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
40075
Lokale Artikelnummer::
BTIU40075
Beschreibung:
The amine reactive succinimidyl ester of MB (methylene blue) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugate will have a blue color and be able to complex with nucleic acids. Methylene blue is a well known redox dye which can be reversibly reduced to its colorless leuco form. Upon oxidation, the blue color of the dye is recovered.
VE:
1 * 5 mg
Artikel-Nr:
(BOSSBS-3831R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3831R-CY3
Lokale Artikelnummer::
BOSSBS-3831R-CY3
Beschreibung:
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1603R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1603R-HRP
Lokale Artikelnummer::
BOSSBS-1603R-HRP
Beschreibung:
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5907R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5907R-A680
Lokale Artikelnummer::
BOSSBS-5907R-A680
Beschreibung:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4047R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4047R-A350
Lokale Artikelnummer::
BOSSBS-4047R-A350
Beschreibung:
ACADM protein is a medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The enzyme catalyzes the initial step of the mitochondrial fatty acid beta oxidation pathway. ACADM expression is induced during periods of fasting, when reliance on fatty acids for energy is increased. Clinical phenotypes are associated with ACADM hereditary deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL63846-500ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
63846-500ML
Lokale Artikelnummer::
SIAL63846-500ML
Beschreibung:
2-Mercaptopyridin-N-oxid Natriumsalz 40% in wässriger Lösung, Sigma-Aldrich®
VE:
1 * 500 mL
Artikel-Nr:
(BOSSBS-13544R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13544R-FITC
Lokale Artikelnummer::
BOSSBS-13544R-FITC
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8551R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8551R-CY5
Lokale Artikelnummer::
BOSSBS-8551R-CY5
Beschreibung:
Nitrotyrosine is a marker for inflammation and nitric oxide (NO) production and is formed in the presence of the active metabolite NO. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage in vivo. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques and chronic renal failure.
VE:
1 * 100 µl
Artikel-Nr:
(MOLEM44132528)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M44132528
Lokale Artikelnummer::
MOLEM44132528
Beschreibung:
3-Hydroxypyridin-N-oxid
VE:
1 * 100 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(EHERC15558000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C15558000
Lokale Artikelnummer::
EHERC15558000
Beschreibung:
4-Nitrochinolin-N-oxid
VE:
1 * 0,1 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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