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6-Chloropyrido[3,4-d]pyrimidin-4(3H)-one
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6-Chloropyrido[3,4-d]pyrimidin-4(3H)-one
Artikel-Nr:
(BOSSBS-11825R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11825R-A488
Lokale Artikelnummer::
BOSSBS-11825R-A488
Beschreibung:
DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-789)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-789
Lokale Artikelnummer::
PRSI91-789
Beschreibung:
Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.
VE:
1 * 0,05 mg
Artikel-Nr:
(APOSOR912126-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR912126-25G
Lokale Artikelnummer::
APOSOR912126-25G
Beschreibung:
5-Ethyl-3-hydroxy-4-methyl-2(5H)-furanon 96%
VE:
1 * 25 g
Artikel-Nr:
(BARN194222)
Lieferant:
BARNSTEAD THERMOLYNE
Hersteller-Artikelnummer::
194222
Lokale Artikelnummer::
BARN194222
Beschreibung:
Stativ für einen stapelbaren Schüttler, 1156×897×752 mm, mit Nivellierfüßen erweitert, Für: MaxQ™ 8000
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-13084R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13084R-HRP
Lokale Artikelnummer::
BOSSBS-13084R-HRP
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13084R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13084R-CY3
Lokale Artikelnummer::
BOSSBS-13084R-CY3
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-FITC
Lokale Artikelnummer::
BOSSBS-11726R-FITC
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-A350
Lokale Artikelnummer::
BOSSBS-11726R-A350
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11489R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11489R-A680
Lokale Artikelnummer::
BOSSBS-11489R-A680
Beschreibung:
TNRC6B is a 1723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukaemias.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2'-Aminoacetophenon 98%
Artikel-Nr:
(EPPE0030076.125)
Lieferant:
EPPENDORF
Hersteller-Artikelnummer::
0030076.125
Lokale Artikelnummer::
EPPE0030076.125
Beschreibung:
Eppendorf epT.I.P.S.® Box 2.0, available with 'Eppendorf Quality' pipette tips or as an empty box, improves lab efficiency with innovative TwinLid® technology, enhanced stackability, and superior ergonomics for safe and organised pipetting.
VE:
1 * 96 ST
Lieferant:
BLD PHARMATECH GMBH
Beschreibung:
4'-Amino-2'-hydroxyacetophenon 96%
Lieferant:
Alfa Aesar
Beschreibung:
4'-Brom-4-chlorbutyrophenon ≥98%
Lieferant:
Sigma-Aldrich
Beschreibung:
Benzylmagnesiumchlorid ∼32% (w/w) 2 mol/l in THF, Sigma-Aldrich®
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-(Benzyloxy)cyclohexanon 96%
Artikel-Nr:
(BOSSBS-11622R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11622R-A488
Lokale Artikelnummer::
BOSSBS-11622R-A488
Beschreibung:
Polycystin-1L3 is a 1,732 amino acid multi-pass membrane protein that contains one PLAT domain, one GPS domain and one C-type lectin domain. Expressed at high levels in placenta and present at lower levels in lung and heart, Polycystin-1L3 is thought to function as an ion-channel regulator that may interact with Polycystin-L and play a role in heteromeric taste channels. The gene encoding Polycystin-1L3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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