Benzoic+acid-acyl-\u03B2-D-glucuronide
Artikel-Nr:
(BOSSBS-12998R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12998R-FITC
Lokale Artikelnummer::
BOSSBS-12998R-FITC
Beschreibung:
Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13312R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13312R-A647
Lokale Artikelnummer::
BOSSBS-13312R-A647
Beschreibung:
GCDH is a 438 amino acid protein that localizes to the mitochondrial matrix and belongs to the acyl-CoA dehydrogenase family. Existing as a homotetramer, GCDH uses FAD as a cofactor to catalyze the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine and L-tryptophan metabolism. While GCDH exists as both a long and short isoform, only the long isoform is a functionally active protein. Defects in the gene encoding GCDH are the cause of glutaric acidemia type I (GA-I), an autosomal recessive disorder that is characterized by the accumulation of glutaconic acid and is associated with such symptoms as progressive dystonia and athetosis due to gliosis and neuronal loss in the basal ganglia.
VE:
1 * 100 µl
Artikel-Nr:
(SIALB8049-5TAB)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
B8049-5TAB
Lokale Artikelnummer::
SIALB8049-5TAB
Beschreibung:
X-Gluc (5-Brom-4-chlor-3-indolyl-ß-D-glucuronid Cyclohexylammoniumsalz, X-GlcA), Sigma-Aldrich®
VE:
1 * 5 Tablet
Artikel-Nr:
(BOSSBS-4888R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4888R-HRP
Lokale Artikelnummer::
BOSSBS-4888R-HRP
Beschreibung:
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3737R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3737R-A750
Lokale Artikelnummer::
BOSSBS-3737R-A750
Beschreibung:
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12998R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12998R-A647
Lokale Artikelnummer::
BOSSBS-12998R-A647
Beschreibung:
Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13312R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13312R
Lokale Artikelnummer::
BOSSBS-13312R
Beschreibung:
GCDH is a 438 amino acid protein that localizes to the mitochondrial matrix and belongs to the acyl-CoA dehydrogenase family. Existing as a homotetramer, GCDH uses FAD as a cofactor to catalyze the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine and L-tryptophan metabolism. While GCDH exists as both a long and short isoform, only the long isoform is a functionally active protein. Defects in the gene encoding GCDH are the cause of glutaric acidemia type I (GA-I), an autosomal recessive disorder that is characterized by the accumulation of glutaconic acid and is associated with such symptoms as progressive dystonia and athetosis due to gliosis and neuronal loss in the basal ganglia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4590R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4590R
Lokale Artikelnummer::
BOSSBS-4590R
Beschreibung:
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5045R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5045R-A555
Lokale Artikelnummer::
BOSSBS-5045R-A555
Beschreibung:
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5045R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5045R-A680
Lokale Artikelnummer::
BOSSBS-5045R-A680
Beschreibung:
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5045R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5045R-A647
Lokale Artikelnummer::
BOSSBS-5045R-A647
Beschreibung:
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13449R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13449R
Lokale Artikelnummer::
BOSSBS-13449R
Beschreibung:
GLYATL2 is a 294 amino acid mitochondrial acyltransferase that transfers the acyl group to the N-terminus of glycine. GLYATL2 can also conjugate a multitude of substrates, including oleoyl-CoA and arachidonoyl-CoA, to form a variety of N-acylglycines. A member of the glycine N-acyltransferase family, GLYATL2 is encoded by a gene that maps to human chromosome 11q12.1. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(10016.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
10016
Lokale Artikelnummer::
BTIU10016
Beschreibung:
X-Gluc (5-Brom-4-chlor-3-indolyl-ß-D-glucuronid Cyclohexylammoniumsalz, X-GlcA)
VE:
1 * 25 mg
Artikel-Nr:
(BOSSBS-4888R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4888R-A488
Lokale Artikelnummer::
BOSSBS-4888R-A488
Beschreibung:
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4888R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4888R-A647
Lokale Artikelnummer::
BOSSBS-4888R-A647
Beschreibung:
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13312R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13312R-CY5
Lokale Artikelnummer::
BOSSBS-13312R-CY5
Beschreibung:
GCDH is a 438 amino acid protein that localizes to the mitochondrial matrix and belongs to the acyl-CoA dehydrogenase family. Existing as a homotetramer, GCDH uses FAD as a cofactor to catalyze the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine and L-tryptophan metabolism. While GCDH exists as both a long and short isoform, only the long isoform is a functionally active protein. Defects in the gene encoding GCDH are the cause of glutaric acidemia type I (GA-I), an autosomal recessive disorder that is characterized by the accumulation of glutaconic acid and is associated with such symptoms as progressive dystonia and athetosis due to gliosis and neuronal loss in the basal ganglia.
VE:
1 * 100 µl
Preis auf Anfrage
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