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2-(1H-Pyrazol-3-yl)acetic+acid
Artikel-Nr:
(BOSSBS-13589R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13589R-CY7
Lokale Artikelnummer::
BOSSBS-13589R-CY7
Beschreibung:
ZNF672 is a 452 amino acid nuclear protein that may be involved in transcriptional regulation. Belonging to the Krüppel C2H2-type zinc-finger protein family, ZNF672 contains 14 C2H2-type zinc fingers. ZNF672 exists as two alternatively spliced isoforms, and is encoded by a gene that maps to human chromosome 1q44. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome, and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7064R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7064R-CY5
Lokale Artikelnummer::
BOSSBS-7064R-CY5
Beschreibung:
Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13589R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13589R-CY3
Lokale Artikelnummer::
BOSSBS-13589R-CY3
Beschreibung:
ZNF672 is a 452 amino acid nuclear protein that may be involved in transcriptional regulation. Belonging to the Krüppel C2H2-type zinc-finger protein family, ZNF672 contains 14 C2H2-type zinc fingers. ZNF672 exists as two alternatively spliced isoforms, and is encoded by a gene that maps to human chromosome 1q44. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome, and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
VE:
1 * 100 µl
Lieferant:
Restek
Beschreibung:
Phasensäulen mit hoher Polarität, Crossbond® Diphenyl-Dimethyl-Polysiloxan, anwendungsspezifisch und speziell auf Triglyceride getestet.
Lieferant:
Alfa Aesar
Beschreibung:
3,3',5,5'-Tetra-tert-butyl-4,4'-diphenoquinone ≥98%
Artikel-Nr:
(KRAF20004.4700)
Lieferant:
Bernd Kraft
Hersteller-Artikelnummer::
20004.4700
Lokale Artikelnummer::
KRAF20004.4700
Beschreibung:
2-Propanol, Gradienten-Qualität für die HPLC
VE:
1 * 2.500 mL
Artikel-Nr:
(BOSSBS-4098R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4098R-CY3
Lokale Artikelnummer::
BOSSBS-4098R-CY3
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6144R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6144R-A680
Lokale Artikelnummer::
BOSSBS-6144R-A680
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilising properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Artikel-Nr:
(420120-250)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
420120-250
Lokale Artikelnummer::
CALB420120-250
Beschreibung:
5-Hydroxy-1,4-naphthochinon (Juglon), Calbiochem®
VE:
1 * 250 mg
Artikel-Nr:
(MAYBSB00887.50)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
SB00887.50
Lokale Artikelnummer::
MAYBSB00887.50
Beschreibung:
1,4-Bis(2,2,2-trifluorethoxy)benzol
VE:
1 * 50 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(MOLEM82971615)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M82971615
Lokale Artikelnummer::
MOLEM82971615
Beschreibung:
1,4-Bis(diphenylphosphino)butan
VE:
1 * 5 g
This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
1,4-Benzodioxan-6-boronsäure, Sigma-Aldrich®
Artikel-Nr:
(MOLE73626632-5G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
73626632-5G
Lokale Artikelnummer::
MOLE73626632-5G
Beschreibung:
Methyl-2,4-dihydroxy-3,6-dimethylbenzoat
VE:
1 * 5 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-4098R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4098R-CY5.5
Lokale Artikelnummer::
BOSSBS-4098R-CY5.5
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4098R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4098R-A647
Lokale Artikelnummer::
BOSSBS-4098R-A647
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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