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DIAGNOSTIC+SYSTEMS+DIASYS
Artikel-Nr:
(BOSSBS-12040R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12040R-CY7
Lokale Artikelnummer::
BOSSBS-12040R-CY7
Beschreibung:
alpha2C-adrenergic receptors (alpha2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. alpha2C-AR can influence Parkinson’s disease, panic disorders, and Huntington disease (HD) progression. A genetic variant in the alpha2C-AR coding region (Del322-325) renders the receptor partially uncoupled from Gi, and is a contributing risk factor for heart failure. alpha2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11980R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11980R-FITC
Lokale Artikelnummer::
BOSSBS-11980R-FITC
Beschreibung:
The calcium binding protein (CaBP) family shares much similarity to calmodulin. It has been shown that CaBP proteins can substitute functionally for, and probably augment the function of, calmodulin. Calcium binding proteins are a crucial part of calcium mediated cellular signal transduction in the central nervous system. There are several members of the family with varying expression patterns. CaBP1 and CaBP2 can be expressed as multiple, alternatively spliced variants in brain and retina. CaBP3, CaBP4 and CaBP 5 are restricted to retinal rod and cone cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7688R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7688R-HRP
Lokale Artikelnummer::
BOSSBS-7688R-HRP
Beschreibung:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3943R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3943R-CY7
Lokale Artikelnummer::
BOSSBS-3943R-CY7
Beschreibung:
G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6867R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6867R-A647
Lokale Artikelnummer::
BOSSBS-6867R-A647
Beschreibung:
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6867R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6867R-CY5
Lokale Artikelnummer::
BOSSBS-6867R-CY5
Beschreibung:
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11980R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11980R-A680
Lokale Artikelnummer::
BOSSBS-11980R-A680
Beschreibung:
The calcium binding protein (CaBP) family shares much similarity to calmodulin. It has been shown that CaBP proteins can substitute functionally for, and probably augment the function of, calmodulin. Calcium binding proteins are a crucial part of calcium mediated cellular signal transduction in the central nervous system. There are several members of the family with varying expression patterns. CaBP1 and CaBP2 can be expressed as multiple, alternatively spliced variants in brain and retina. CaBP3, CaBP4 and CaBP 5 are restricted to retinal rod and cone cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11980R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11980R-CY3
Lokale Artikelnummer::
BOSSBS-11980R-CY3
Beschreibung:
The calcium binding protein (CaBP) family shares much similarity to calmodulin. It has been shown that CaBP proteins can substitute functionally for, and probably augment the function of, calmodulin. Calcium binding proteins are a crucial part of calcium mediated cellular signal transduction in the central nervous system. There are several members of the family with varying expression patterns. CaBP1 and CaBP2 can be expressed as multiple, alternatively spliced variants in brain and retina. CaBP3, CaBP4 and CaBP 5 are restricted to retinal rod and cone cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7688R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7688R-A680
Lokale Artikelnummer::
BOSSBS-7688R-A680
Beschreibung:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13391R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13391R-A555
Lokale Artikelnummer::
BOSSBS-13391R-A555
Beschreibung:
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7525R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7525R-CY7
Lokale Artikelnummer::
BOSSBS-7525R-CY7
Beschreibung:
This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11719R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11719R-A647
Lokale Artikelnummer::
BOSSBS-11719R-A647
Beschreibung:
Calcyon is a single transmembrane protein that interacts with D1 dopamine receptors. Dopamine is a neurotransmitter that regulates synaptic transmission involved in learning and memory. D1 receptors, the most abundant dopamine receptor in the central nervous system, appear to modulate the activity of D2 dopamine receptors, mediate various behavioural responses, and regulate neuron growth and differentiation. Calcyon is present in neuronal cell bodies and processes of the cortex and hippocampus, and it is especially abundant in pyramidal neurons. Interaction of Calcyon with D1 receptors results in a release of intracellular calcium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12040R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12040R-FITC
Lokale Artikelnummer::
BOSSBS-12040R-FITC
Beschreibung:
alpha2C-adrenergic receptors (alpha2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. alpha2C-AR can influence Parkinson’s disease, panic disorders, and Huntington disease (HD) progression. A genetic variant in the alpha2C-AR coding region (Del322-325) renders the receptor partially uncoupled from Gi, and is a contributing risk factor for heart failure. alpha2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6804R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6804R-HRP
Lokale Artikelnummer::
BOSSBS-6804R-HRP
Beschreibung:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6804R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6804R-A488
Lokale Artikelnummer::
BOSSBS-6804R-A488
Beschreibung:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3943R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3943R-A647
Lokale Artikelnummer::
BOSSBS-3943R-A647
Beschreibung:
G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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