Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
Artikel-Nr:
(1613804.)
Lieferant:
USP
Hersteller-Artikelnummer::
1613804
Lokale Artikelnummer::
USPH1613804
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 1 g
Lieferant:
Thermo Scientific
Beschreibung:
L(+)-Kaliumnatriumtartrat Tetrahydrat ACS
Lieferant:
Sigma-Aldrich
Beschreibung:
L(+)-Weinsäure ≥99,5% ACS, Sigma-Aldrich®
Artikel-Nr:
(662-0889)
Lieferant:
Thermo Orion
Hersteller-Artikelnummer::
9863BN
Lokale Artikelnummer::
ORIO9863BN
Beschreibung:
This bevel needle-tipped 16-gauge glass body combination electrode can be used to measure pH by piercing septa.
VE:
1 * 1 ST
Artikel-Nr:
(EHERXA13356300ME)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
XA13356300ME
Lokale Artikelnummer::
EHERXA13356300ME
Beschreibung:
Organic Standard, m-Ethyltoluol 100 µg/ml in Methanol, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(662-2458)
Lieferant:
ENDRESS HAUSER
Hersteller-Artikelnummer::
CPL51E-1061/0
Lokale Artikelnummer::
ENDRCPL51E-1061/0
Beschreibung:
Potentiometric pH glass sensor with plastic shaft for laboratory measurement and random sampling in the process. Connectable via inductive, digital connection with Memosens technology.
VE:
1 * 1 ST
Artikel-Nr:
(SIAL186562-100ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
186562-100ML
Lokale Artikelnummer::
SIAL186562-100ML
Beschreibung:
Tetrahydrofuran stabilisiert, Sigma-Aldrich®
VE:
1 * 100 mL
Lieferant:
Alfa Aesar
Beschreibung:
Temsirolimus ≥99%
Artikel-Nr:
(462-0108)
Lieferant:
NICKEL ELECTRO
Hersteller-Artikelnummer::
NE4-14T
Lokale Artikelnummer::
NICKNE4-14T
Beschreibung:
These thermostatically controlled analogue stirred baths have a corrosion resistant stainless steel tank and durable outer case. Immersed components are corrosion resistant.
VE:
1 * 1 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
Phosphor, rot, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-1135R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1135R-FITC
Lokale Artikelnummer::
BOSSBS-1135R-FITC
Beschreibung:
c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1135R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1135R-CY7
Lokale Artikelnummer::
BOSSBS-1135R-CY7
Beschreibung:
c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-554)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-554
Lokale Artikelnummer::
PRSI91-554
Beschreibung:
Vitelline membrane outer layer protein 1 homolog (VMO1) belongs to the VMO1 family is a 202 amino acid secreted protein. Exact function not known, component of the outer membrane of the vitelline layer of the egg. Seems to be able to synthesize N-acetylchito-oligosaccharides (n=14-15) from hexasaccharides of N-acetylglucosamine in a manner similar to the transferase activity of lysozyme.
VE:
1 * 50 µG
Lieferant:
Mettler - Toledo
Beschreibung:
Ideal für kritische Proben wie Suspensionen oder Proben unbekannter Zusammensetzung (z.B. Abwasser).
Artikel-Nr:
(662-0765)
Lieferant:
Thermo Orion
Hersteller-Artikelnummer::
900100
Lokale Artikelnummer::
ORIO900100
Beschreibung:
This reference half-cell electrode helps to precisely measure with ion-selective electrodes. Ideal for ISE determinations and routine pH measurements with Orion 910100 electrodes.
VE:
1 * 1 ST
Lieferant:
COMBI-BLOCKS
Beschreibung:
3-Chlor-5-methylphenylboronsäure
Preis auf Anfrage
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