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1-Hydroxy-4-nitroisoquinoline
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1-Hydroxy-4-nitroisoquinoline
Artikel-Nr:
(BOSSBS-12926R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12926R-CY7
Lokale Artikelnummer::
BOSSBS-12926R-CY7
Beschreibung:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, and a variety of procarcinogenic compounds to their activated forms, including polycyclic aromatic hydrocarbons. Promotes angiogenesis by removing cellular oxygenation products, thereby decreasing oxidative stress, release of antiangiogenic factor THBS2, then allowing endothelial cells migration, cell adhesion and capillary morphogenesis. These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis. Plays an important role in the regulation of perivascular cell proliferation, migration, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, during angiogenesis. Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12926R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12926R-CY3
Lokale Artikelnummer::
BOSSBS-12926R-CY3
Beschreibung:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, and a variety of procarcinogenic compounds to their activated forms, including polycyclic aromatic hydrocarbons. Promotes angiogenesis by removing cellular oxygenation products, thereby decreasing oxidative stress, release of antiangiogenic factor THBS2, then allowing endothelial cells migration, cell adhesion and capillary morphogenesis. These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis. Plays an important role in the regulation of perivascular cell proliferation, migration, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, during angiogenesis. Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD306171-500G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD306171-500G
Lokale Artikelnummer::
BLDPBD306171-500G
Beschreibung:
Eosin G 97%
VE:
1 * 500 g
Artikel-Nr:
(SERA14980.02)
Lieferant:
Serva
Hersteller-Artikelnummer::
14980.02
Lokale Artikelnummer::
SERA14980.02
Beschreibung:
Bestatin ([S-(R*,S*)]-N-(3-amino-2-hydroxy-4-phenylbutyroyl)-L-leucine)
VE:
1 * 5 mg
 This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
5-Hydroxy-2-indolcarbonsäure, Sigma-Aldrich®
Artikel-Nr:
(230251-25G)
Lieferant:
SIGMA ALDRICH MICROSCOPY
Hersteller-Artikelnummer::
230251-25G
Lokale Artikelnummer::
SIAM230251-25G
Beschreibung:
Eosin Y is a xanthene dye and is used for the differential staining of connective tissue and cytoplasm. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. It is also used as a background stain, thereby giving contrast to the nuclear stains.
VE:
1 * 25 g
Lieferant:
Thermo Scientific
Beschreibung:
2-Thioxo-2,3-dihydro-4(1H)-pyrimidinon 99%
Lieferant:
Merck
Beschreibung:
EMSURE® grade solvents are suitable for a broad spectrum of classical lab applications, and are frequently used in regulated and highly demanding lab applications. EMSURE® provides worldwide best and most extensive product specifications. We declare our EMSURE® range to be in compliance with the ACS, with the reagent part of the European Pharmacopoeia (Reag. Ph Eur) and also with the ISO standards.
Artikel-Nr:
(BOSSBS-6560R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6560R-A555
Lokale Artikelnummer::
BOSSBS-6560R-A555
Beschreibung:
The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6560R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6560R-A647
Lokale Artikelnummer::
BOSSBS-6560R-A647
Beschreibung:
The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
7-Hydroxy-3,7-dimethyloctanal, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-6560R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6560R-CY7
Lokale Artikelnummer::
BOSSBS-6560R-CY7
Beschreibung:
The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6560R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6560R-A350
Lokale Artikelnummer::
BOSSBS-6560R-A350
Beschreibung:
The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Äsculin Sesquihydrat ≥97%
Artikel-Nr:
(SIAL482609-500MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
482609-500MG
Lokale Artikelnummer::
SIAL482609-500MG
Beschreibung:
Bestatin ([S-(R*,S*)]-N-(3-amino-2-hydroxy-4-phenylbutyroyl)-L-leucine)
VE:
1 * 500 mg
Artikel-Nr:
(BOSSBS-6560R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6560R-CY3
Lokale Artikelnummer::
BOSSBS-6560R-CY3
Beschreibung:
The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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