Dimethyl+2,5-dibromoterephthalate
Artikel-Nr:
(BOSSBS-4098R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4098R-A488
Lokale Artikelnummer::
BOSSBS-4098R-A488
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4098R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4098R-A750
Lokale Artikelnummer::
BOSSBS-4098R-A750
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilising properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4098R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4098R-FITC
Lokale Artikelnummer::
BOSSBS-4098R-FITC
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
7-Isopropyl-1,4-dimethylazulen, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
3,4-Dimethoxy-3-cyclobuten-1,2-dion, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
2-Propanol, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
7-Aminoactinomycin (7-AAD), Sigma-Aldrich®
Artikel-Nr:
(MOLEM31244850)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M31244850
Lokale Artikelnummer::
MOLEM31244850
Beschreibung:
Riboflavin-5'-phosphat Natriumsalz Dihydrat
VE:
1 * 10 g
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Lieferant:
Thermo Scientific
Beschreibung:
3,4-Dimethoxy-3-cyclobuten-1,2-dion
Artikel-Nr:
(BOSSBS-4098R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4098R-CY3
Lokale Artikelnummer::
BOSSBS-4098R-CY3
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6144R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6144R-A680
Lokale Artikelnummer::
BOSSBS-6144R-A680
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilising properties and the half-life of their target mRNAs.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
2-Propanol ≥70% (v/v), SAFC®
Artikel-Nr:
(PROONMIAD621)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
NMIAD621
Lokale Artikelnummer::
PROONMIAD621
Beschreibung:
Purity estimate obtained by quantitative NMR against an internal standard of dimethyl sulphone is 84,6 ± 1,5% mass fraction, (95% coverage interval). Supporting evidence is provided by HPLC with UV detection, Karl Fischer analysis and theromogravimetric analysis.
VE:
1 * 1 mg
Artikel-Nr:
(FLUO021613-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
021613-5G
Lokale Artikelnummer::
FLUO021613-5G
Beschreibung:
4-(N,N-Dimethylamino)phenylboronsäurepinakolester
VE:
1 * 5 g
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Lieferant:
Thermo Scientific
Beschreibung:
2-Fluor-m-xylol
Lieferant:
COMBI-BLOCKS
Beschreibung:
3-(N,N-Dimethylamino)phenylboronsäurepinakolester
Preis auf Anfrage
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