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Doxorubicin
Artikel-Nr:
(API-05)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
API-05
Lokale Artikelnummer::
GENOAPI-05
Beschreibung:
Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).
VE:
1 * 50 µl
Artikel-Nr:
(PHR1789-200MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
PHR1789-200MG
Lokale Artikelnummer::
SUPLPHR1789-200MG
Beschreibung:
Organic Standard, Doxorubicin Hydrochloride
VE:
1 * 200 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Inhibitor of RNA synthesis.
Artikel-Nr:
(1225703.)
Lieferant:
USP
Hersteller-Artikelnummer::
1225703
Lokale Artikelnummer::
USPH1225703
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 50 mg
Artikel-Nr:
(API-16S)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
API-16S
Lokale Artikelnummer::
GENOAPI-16S
Beschreibung:
Apoptosis inducers are used for induction of apoptosis in cultured cells. The selection of apoptosis inducers include actinomycin D, camptothecin, cycloheximide, dexamethasone, doxorubicin and etoposide.
VE:
1 * 1 SET
Artikel-Nr:
(BOSSBS-3523R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3523R-HRP
Lokale Artikelnummer::
BOSSBS-3523R-HRP
Beschreibung:
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7953R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7953R-HRP
Lokale Artikelnummer::
BOSSBS-7953R-HRP
Beschreibung:
Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7953R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7953R-A680
Lokale Artikelnummer::
BOSSBS-7953R-A680
Beschreibung:
Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7953R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7953R-A750
Lokale Artikelnummer::
BOSSBS-7953R-A750
Beschreibung:
Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
VE:
1 * 100 µl
Artikel-Nr:
(ICNA0215910110)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
0215910110
Lokale Artikelnummer::
ICNA0215910110
Beschreibung:
Doxorubicin Hydrochloride is a chemotherapeutic, antitumour, immunosuppressive, and antibiotic agent.
VE:
1 * 10 mg
Lieferant:
Alfa Aesar
Beschreibung:
Doxorubicin hydrochloride is an anti-tumour, anti-neoplastic and anti-biotic agent that inhibits DNA topoisomerase II. It also inhibits nucleic acid synthesis and induces apoptosis.
Artikel-Nr:
(PROOBP990)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
BP990
Lokale Artikelnummer::
PROOBP990
Beschreibung:
Organic Standard, Doxorubicin hydrochloride assay standard
VE:
1 * 100 mg
Lieferant:
Cayman Chemical
Beschreibung:
Doxorubicin is an anthracycline anti-tumour antibiotic which involves in inhibition of DNA topoisomerase II by inducing double-stranded DNA breaks. It is also involved in the inhibition of nucleic acid synthesis by intercalating within DNA. The accumulation of the p53 tumour suppressor protein leads to the apoptosis in cells.
Artikel-Nr:
(PRSI79-673)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-673
Lokale Artikelnummer::
PRSI79-673
Beschreibung:
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5815)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5815
Lokale Artikelnummer::
PRSI5815
Beschreibung:
FOXO4 Antibody: FOXO4 is a ubiquitously expressed protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. In the absence of PI3K/AKT activation, FOXO4 localizes in the nucleus where it functions as a transcription factor. FOXO4 can also be phosphorylated by JNK following induction of reactive oxygen species (ROS), resulting in transcriptional activation and the induction of a negative feedback mechanism to counteract the ROS. It is through this mechanism that FOXO4 is thought to sensitize cancer cells to doxorubicin-mediated toxicity.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5817)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5817
Lokale Artikelnummer::
PRSI5817
Beschreibung:
FOXO4 Antibody: FOXO4 is a ubiquitously expressed protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. In the absence of PI3K/AKT activation, FOXO4 localizes in the nucleus where it functions as a transcription factor. FOXO4 can also be phosphorylated by JNK following induction of reactive oxygen species (ROS), resulting in transcriptional activation and the induction of a negative feedback mechanism to counteract the ROS. It is through this mechanism that FOXO4 is thought to sensitize cancer cells to doxorubicin-mediated toxicity.
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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