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Benzoic+acid-acyl-\u03B2-D-glucuronide
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Benzoic+acid-acyl-\u03B2-D-glucuronide
Artikel-Nr:
(BOSSBS-13375R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13375R-CY7
Lokale Artikelnummer::
BOSSBS-13375R-CY7
Beschreibung:
The GLIPR1 family consists of three core members, designated GLIPR1, GLIPR1L1 (GLIPR1-like protein 1) and GLIPR1L2, which form a distinct subgroup within the cysteine-rich secretory protein (CRISP), antigen 5 and pathogenesis-related 1 (CAP) superfamily. Each member of the CAP superfamily has a conserved N-terminal CAP domain and a distinct C-terminal extension. CAP superfamily proteins are hypothesized to have roles in immunity, cell adhesion, carcinogenesis and male fertility. GLIPR1L1 is a 242 amino acid secreted protein. Highly expressed in testis, GLIPR1L1 exists as two isoforms produced by alternative splicing events. GLIPR1L1 is encoded by a gene that maps to human chromosome 12q21.1 and mouse chromosome 10 D2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11229R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11229R-CY7
Lokale Artikelnummer::
BOSSBS-11229R-CY7
Beschreibung:
OTUB1 is a 271 amino acid protein that contains one OTU (ovarian tumor) domain and belongs to the OTU family of predicted cysteine proteases. Expressed as two isoforms (one of which is present throughout the body and the other of which is present only in lymphoid tissues), OTUB1 functions as a hydrolase that can remove ubiquitin residues from target proteins, thereby preventing protein degradation and playing an important role in protein turnover. OTUB1 interacts with GRAIL and, via this interaction, plays a role in the regulation and the induction of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to their cognate antigens. Due to its interaction with GRAIL, OTUB1 is an important regulator of immune responses in secondary lymphoid organs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11173R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11173R
Lokale Artikelnummer::
BOSSBS-11173R
Beschreibung:
Prenylation and methylation are two forms of protein modification, both of which are important for a variety of functions, including membrane attachment, protein-protein interactions and signaling events. NARF (nuclear prelamin A recognition factor), also known as IOP2, is a 456 amino acid nuclear protein that belongs to the NARF family. Expressed ubiquitously with highest expression in heart, skeletal muscle and brain, NARF binds to the C-terminal end of prenylated prelamin A and may be a member of a prelamin A-containing endoprotease complex. Additionally, via its association with prelamin A, NARF may be involved in heterochromatin organization. NARF is expressed as three isoforms due to alternative splicing events and, upon DNA damage, may be phosphorylated by ATM or ATR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-16723R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-16723R
Lokale Artikelnummer::
BOSSBS-16723R
Beschreibung:
SHKBP1 is a 707 amino acid protein belonging to the KCTD3 family. Acting downstream of Flt-3/Flk-2, SHKBP1 interacts with CIN85. SHKBP1 contains a BTB/POZ domain, which is involved in ring canal formation and chromatin folding, and five WB repeats. SHKBP1 exists as two alternatively spliced isoforms and maps to human chromosome 19q13.2. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6805R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6805R-CY5
Lokale Artikelnummer::
BOSSBS-6805R-CY5
Beschreibung:
CLUAP1 (Clusterin associated protein 1) is a 413 amino acid nuclear protein that exists as two alternatively spliced isoforms that interact with Clusterin. CLUAP1 is suggested to play a role in apoptosis and cell proliferation, and is expressed in testis, thrachea and thyroid, with low levels found in adrenal gland and spinal cord. The gene encoding CLUAP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11173R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11173R-A680
Lokale Artikelnummer::
BOSSBS-11173R-A680
Beschreibung:
Prenylation and methylation are two forms of protein modification, both of which are important for a variety of functions, including membrane attachment, protein-protein interactions and Signalling events. NARF (nuclear prelamin A recognition factor), also known as IOP2, is a 456 amino acid nuclear protein that belongs to the NARF family. Expressed ubiquitously with highest expression in heart, skeletal muscle and brain, NARF binds to the C-terminal end of prenylated prelamin A and may be a member of a prelamin A-containing endoprotease complex. Additionally, via its association with prelamin A, NARF may be involved in heterochromatin organization. NARF is expressed as three isoforms due to alternative splicing events and, upon DNA damage, may be phosphorylated by ATM or ATR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13390R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13390R
Lokale Artikelnummer::
BOSSBS-13390R
Beschreibung:
GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12212R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12212R-CY7
Lokale Artikelnummer::
BOSSBS-12212R-CY7
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF342 (zinc finger protein 342), also known as Zinc finger protein 296, is a 475 amino acid nuclear protein that contains six C2H2-type zinc fingers through which it is thought to be involved in DNA-binding and transcriptional regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9393R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9393R
Lokale Artikelnummer::
BOSSBS-9393R
Beschreibung:
P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13366R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13366R
Lokale Artikelnummer::
BOSSBS-13366R
Beschreibung:
GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8423R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8423R-CY7
Lokale Artikelnummer::
BOSSBS-8423R-CY7
Beschreibung:
Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL1 (bactericidal/permeability-increasing protein-like 1) is a 458 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL1 is primarily expressed at low levels in tonsil tissue, it has been found to be upregulated in hypertrophic tonsils, suggesting that it may play a role in the pathogenesis of inflamed disease tissue.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11358R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11358R-A750
Lokale Artikelnummer::
BOSSBS-11358R-A750
Beschreibung:
RIMS-binding proteins (RIM-BPs) serve as adaptors during vesicle fusion and release by forming links between synaptic-vesicle fusion apparatuses and calcium channels. Specifically, RIM-BP2 (RIMS binding protein 2), also known as RBP2, is a 1052 amino acid protein that links L-type Ca⁺⁺ CP Alpha1D, N-type Ca⁺⁺ CP Alpha1B, Rim1 and Rim2 during synaptic transmission. RIM-BP2 contains three fibronectin type-III domains and three SH3 domains, which are used to mediate binding to a proline-rich motifs. Existing as three alternatively spliced isoforms, RIM-BP2 is encoded by a gene that maps to human chromosome 12q24.33 and mouse chromosome 5 G1.3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11358R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11358R-A680
Lokale Artikelnummer::
BOSSBS-11358R-A680
Beschreibung:
RIMS-binding proteins (RIM-BPs) serve as adaptors during vesicle fusion and release by forming links between synaptic-vesicle fusion apparatuses and calcium channels. Specifically, RIM-BP2 (RIMS binding protein 2), also known as RBP2, is a 1052 amino acid protein that links L-type Ca⁺⁺ CP Alpha1D, N-type Ca⁺⁺ CP Alpha1B, Rim1 and Rim2 during synaptic transmission. RIM-BP2 contains three fibronectin type-III domains and three SH3 domains, which are used to mediate binding to a proline-rich motifs. Existing as three alternatively spliced isoforms, RIM-BP2 is encoded by a gene that maps to human chromosome 12q24.33 and mouse chromosome 5 G1.3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13222R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13222R-A750
Lokale Artikelnummer::
BOSSBS-13222R-A750
Beschreibung:
FSD2 is a 749 amino acid protein containing one B30.2/SPRY domain and two fibronectin type-III domains. The gene encoding FSD2 maps to human chromosome 15q25.2. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and consists of about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are also associated with chromosome 15.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12405R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12405R-CY3
Lokale Artikelnummer::
BOSSBS-12405R-CY3
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11110R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11110R
Lokale Artikelnummer::
BOSSBS-11110R
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH17 is a 1,159 amino acid single-pass type I membrane protein that contains six cadherin domains. Expressed as multiple alternatively spliced isoforms, PCDH17 is thought to function as a calcium-dependent cell adhesion protein that may play a role in establishing cell-cell connections within brain tissue. The gene encoding PCDH17 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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