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5-Amino-2-nitrobenzoes\\\\u00E4ure
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5-Amino-2-nitrobenzoes\\\\u00E4ure
Artikel-Nr:
(BOSSBS-11665R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11665R-A680
Lokale Artikelnummer::
BOSSBS-11665R-A680
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of clathrin binding adaptin proteins and two smaller subunits known as AP50 and AP17. The Alpha- and Beta-Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. Alpha-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP180 (also designated AP-3 or F1-20) is a synapse-specific clathrin assembly protein. The protein CALM (clathrin assembly protein lymphoid myeloid leukaemia) is highly homologous to AP180 and may also be involved in clathrin assembly.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)acrylic acid
Artikel-Nr:
(BLDPBD41374-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD41374-250MG
Lokale Artikelnummer::
BLDPBD41374-250MG
Beschreibung:
5,7-Dibrom-2,3-dihydrothieno[3,4-b][1,4]dioxin 95%
VE:
1 * 250 mg
Artikel-Nr:
(APOSOR310893-500MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR310893-500MG
Lokale Artikelnummer::
APOSOR310893-500MG
Beschreibung:
3-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehyde
VE:
1 * 500 mg
Artikel-Nr:
(APOSOR310664-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR310664-1G
Lokale Artikelnummer::
APOSOR310664-1G
Beschreibung:
3-(3-Methylphenyl)-1,4-diazaspiro[4.5]dec-3-ene-2-thione
VE:
1 * 1 g
Artikel-Nr:
(APOSPC430564-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC430564-250MG
Lokale Artikelnummer::
APOSPC430564-250MG
Beschreibung:
8'-Fluoro-5'-hydroxy-spiro[cyclohexane-1,4'(1'h)-quinazolin]-2'(3'h)-one
VE:
1 * 250 mg
Artikel-Nr:
(BLDPBD254489-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD254489-1G
Lokale Artikelnummer::
BLDPBD254489-1G
Beschreibung:
(2,3-Dihydrothieno[3,4-b][1,4]dioxin-2-yl)methanol 95%
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD81958-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD81958-250MG
Lokale Artikelnummer::
BLDPBD81958-250MG
Beschreibung:
3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid 95%
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-0344R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0344R-A750
Lokale Artikelnummer::
BOSSBS-0344R-A750
Beschreibung:
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8333R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-A750
Lokale Artikelnummer::
BOSSBS-8333R-A750
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localises on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognises retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8333R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-HRP
Lokale Artikelnummer::
BOSSBS-8333R-HRP
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid
Artikel-Nr:
(BOSSBS-2835R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2835R-CY3
Lokale Artikelnummer::
BOSSBS-2835R-CY3
Beschreibung:
The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2835R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2835R-CY5
Lokale Artikelnummer::
BOSSBS-2835R-CY5
Beschreibung:
The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5814R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5814R-A555
Lokale Artikelnummer::
BOSSBS-5814R-A555
Beschreibung:
Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1228R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1228R-A647
Lokale Artikelnummer::
BOSSBS-1228R-A647
Beschreibung:
Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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