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4-Brom-3-methoxybenzamid
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4-Brom-3-methoxybenzamid
Artikel-Nr:
(BOSSBS-11956R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11956R-FITC
Lokale Artikelnummer::
BOSSBS-11956R-FITC
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK3 (SLIT and NTRK-like family, member 3) is a 977 amino acid single-pass type I membrane protein that contains 20 LRR repeats and belongs to the SLITRK family. Expressed at highest levels in cerebral cortex, SLITRK3 is also found in adult and fetal neural tissues and some astrocytic brain tumors. SLITRK3 functions to suppress neurite outgrowth and plays a role in the regulation of neuronal function. SLITRK3 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1302R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1302R-HRP
Lokale Artikelnummer::
BOSSBS-1302R-HRP
Beschreibung:
Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
VE:
1 * 100 µl
Artikel-Nr:
(MOLEM58031924)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M58031924
Lokale Artikelnummer::
MOLEM58031924
Beschreibung:
3-Amino-4-hydroxybenzoesäure
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Amino-2-fluorphenylboronsäurepinakolester
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Amino-5-methylphenylboronsäurepinakolester
Artikel-Nr:
(EHERC10228000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C10228000
Lokale Artikelnummer::
EHERC10228000
Beschreibung:
2-Amino-5-methylbenzolsulfonsäure
VE:
1 * 0,1 g
Lieferant:
Thermo Scientific
Beschreibung:
2-Amino-4-methylpyridin
Artikel-Nr:
(APOSOR10562-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR10562-1G
Lokale Artikelnummer::
APOSOR10562-1G
Beschreibung:
4-(Methylsulphonylamino)benzeneboronic acid 95%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-12311R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12311R-A647
Lokale Artikelnummer::
BOSSBS-12311R-A647
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeasts and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5808R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5808R-CY7
Lokale Artikelnummer::
BOSSBS-5808R-CY7
Beschreibung:
CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.PathwayOrganosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5808R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5808R
Lokale Artikelnummer::
BOSSBS-5808R
Beschreibung:
CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.PathwayOrganosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.
VE:
1 * 100 µl
Artikel-Nr:
(FLUO018173-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
018173-5G
Lokale Artikelnummer::
FLUO018173-5G
Beschreibung:
3-Amino-5-tert-butylisoxazol
VE:
1 * 5 g
This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
2-Amino-9-fluorenon, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-12438R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12438R
Lokale Artikelnummer::
BOSSBS-12438R
Beschreibung:
LRRFIP2 is a 721 amino acid protein that belongs to the LRRFIP family. Ubiquitously expressed, LRRFIP2 acts as an activator of the Wnt signaling pathway and as a positive regulator of NFâ…¹B activity. LRRFIP2 may be involved in regulating cytokine production in macrophages, suggesting a functional role in the TLR4-mediated inflammatory response. Three isoforms of LRRFIP2 exists due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL516392-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
516392-1G
Lokale Artikelnummer::
SIAL516392-1G
Beschreibung:
2-Amino-5-iodpyridin, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(MOLE11848882-100G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
11848882-100G
Lokale Artikelnummer::
MOLE11848882-100G
Beschreibung:
2-Amino-5-methylthiazol
VE:
1 * 100 g
This is a MarketSource item. Additional charges may apply
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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