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Ethyl-2-naphthoyl+formate
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Ethyl-2-naphthoyl+formate
Lieferant:
Thermo Scientific
Beschreibung:
Ethyl-4-amino-3,5-diiodbenzoat
Artikel-Nr:
(FLUO021483-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
021483-5G
Lokale Artikelnummer::
FLUO021483-5G
Beschreibung:
Ethyl-2-amino-4-phenyl-3-thiophencarboxylat
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Brom-N-(2-(TBDMSO)ethyl)benzolsulfonamid
Lieferant:
BIONET RESEARCH
Beschreibung:
Ethyl-6-fluor-4-hydroxychinolin-3-carboxylat
Artikel-Nr:
(BOSSBS-9191R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9191R-HRP
Lokale Artikelnummer::
BOSSBS-9191R-HRP
Beschreibung:
PDZRN3 contains a RING-finger motif in its N-terminal region, two PDZ domains in its central region and a consensus-binding motif for PDZ domains at its C-terminus. It was identified in silico as a homolog of the protein known as LNX1 or SEMCAP1, which possesses ubiquitin ligase activity and binds the membrane protein Semaphorin 4C. However, PDZRN3 itself has not previously been characterized. We have now evaluated the properties and functions of PDZRN3. The PDZRN3 gene was shown to be expressed in various human tissues including the heart, skeletal muscle and liver and its expression in mouse skeletal muscle was developmentally regulated. Both the differentiation of C2C12 mouse skeletal myoblasts into myotubes and injury-induced muscle regeneration in vivo were found to be accompanied by up-regulation of PDZRN3. The differentiation-associated increase in the expression of PDZRN3 in C2C12 cells follows that of myogenin and precedes that of myosin heavy chain. Depletion of PDZRN3 by RNA interference inhibited the formation of myotubes as well as the associated up-regulation of myosin heavy chain in C2C12 cells. Our data suggest that PDZRN3 plays an essential role in the differentiation of myoblasts into myotubes by acting either downstream or independently of myogenin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3406R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3406R-CY3
Lokale Artikelnummer::
BOSSBS-3406R-CY3
Beschreibung:
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromosome proteins are conserved in eukaryotes and can lead to mitotic chromosome segregation defects, suggesting a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. A number of cellular factors interact with hSMC1/hSMC3 during cell cycle. The major population of hSMC1/hSMC3 is in a compex with hRAD21 forming the human cohesion complex. Human cohesion complex associates with chromosomes which peaks at S phase and dissociates from chromosomes during G2/M transition. In addition, a subpopulation of hSMC1/hSMC3 associates tightly with nuclear matrix and centrosomes during interphase. A subset of hSMC1/hSMC3 is localized to spindle poles, spindles and kinetochores during mitosis when cohesin is in the cytoplasm. hSMC1/hSMC3 is required for spindle aster formation in vitro and reacts with nuclear mitotic apparatus protein in vivo.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1335R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1335R-CY5
Lokale Artikelnummer::
BOSSBS-1335R-CY5
Beschreibung:
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0485R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0485R-CY5
Lokale Artikelnummer::
BOSSBS-0485R-CY5
Beschreibung:
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3751R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3751R-CY5.5
Lokale Artikelnummer::
BOSSBS-3751R-CY5.5
Beschreibung:
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in Ran disrupt DNA synthesis. Because of its many functions, it is likely that Ran interacts with several other proteins. Ran regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. Ran could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of Ran-GTP around chromatin which, in turn, induces the local nucleation of microtubules. Ran is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). Ran coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
Ethyl-4-hydroxy-8-methoxychinolin-3-carboxylat
Artikel-Nr:
(COBBHC-2213-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
HC-2213-1G
Lokale Artikelnummer::
COBBHC-2213-1G
Beschreibung:
Ethyl-6-chlor-4-hydroxychinolin-3-carboxylat
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Lieferant:
COMBI-BLOCKS
Beschreibung:
Ethyl-2-amino-5-oxazolcarboxylat
Lieferant:
GA
Beschreibung:
These labels, provided in A4 sheet format, are compatible with both desktop laser and inkjet printers. Perfect for general-use applications in labs, offices, and warehouses.
Artikel-Nr:
(PRSI7257)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7257
Lokale Artikelnummer::
PRSI7257
Beschreibung:
FOXA2 Antibody: FOXA2 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. FOXA2 was initially identified through library screening as a closely related homolog of FOXA1. Both FOXA2 and FOXA1 act as transcriptional activators in adult liver and also play a role in body axis formation, neural tube patterning and definitive endoderm formation during gastrulation.
VE:
1 * 100 µG
Lieferant:
Thermo Scientific
Beschreibung:
Ethyl-2-(5-brom-2-thienyl)-2-oxoacetat
Lieferant:
COMBI-BLOCKS
Beschreibung:
Ethyl-3,6-dibrompicolinat
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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