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Ethyl-2-naphthoyl+formate
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Ethyl-2-naphthoyl+formate
Artikel-Nr:
(BOSSBS-2743R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2743R-A555
Lokale Artikelnummer::
BOSSBS-2743R-A555
Beschreibung:
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3079R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3079R
Lokale Artikelnummer::
BOSSBS-3079R
Beschreibung:
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Activates several signaling pathways in response to ligand binding. Phosphorylates PIK3R1, PLCG2, GRB2, SLA2 and CBL. Activation of PLCG2 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, that then lead to the activation of protein kinase C family members, especially PRKCD. Phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leads to activation of the AKT1 signaling pathway. Activated CSF1R also mediates activation of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, and of the SRC family kinases SRC, FYN and YES1. Activated CSF1R transmits signals both via proteins that directly interact with phosphorylated tyrosine residues in its intracellular domain, or via adapter proteins, such as GRB2. Promotes activation of STAT family members STAT3, STAT5A and/or STAT5B. Promotes tyrosine phosphorylation of SHC1 and INPP5D/SHIP-1.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI79-721)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-721
Lokale Artikelnummer::
PRSI79-721
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µG
Artikel-Nr:
(1.08445.0250)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.08445.0250
Lokale Artikelnummer::
MERC1.08445.0250
Beschreibung:
EDTA Trikaliumsalz Dihydrat, Supelco®
VE:
1 * 250 g
Artikel-Nr:
(PRSI90-332)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-332
Lokale Artikelnummer::
PRSI90-332
Beschreibung:
DLL3 (Delta-like protein 3; Delta3) inhibits primary neurogenesis. It plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 binds and activates Notch-1 or another Notch receptor. Defects in DLL3 are the cause of spondylocostal dysostosis type 1 (SCDO1).
VE:
1 * 10 µG
Artikel-Nr:
(PRSI26-240)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-240
Lokale Artikelnummer::
PRSI26-240
Beschreibung:
DRGX is a transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain.
VE:
1 * 50 µG
Lieferant:
HOEFER ELECTROPHORESIS
Beschreibung:
Das vertikale Mini-Elektrophoresesystem SE260 Mighty Small II Deluxe vereint die Vorteile von kleinem Format und effizienter Kühlung für ein schnelles Screening von Proteinen und Nukleinsäuren.
Artikel-Nr:
(PRSI33-439)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-439
Lokale Artikelnummer::
PRSI33-439
Beschreibung:
CD99 is involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. [UniProt].
VE:
1 * 100 µG
New Product
Lieferant:
Thermo Scientific
Beschreibung:
Cross linkers are used for the identification of near-neighbour protein relationships and ligand-receptor interactions. Homobifunctional, amine-reactive NHS esters or imidates, and heterobifunctional, amine-reactive, photoactivatable phenyl azides are the most commonly used crosslinkers for these applications.
Artikel-Nr:
(PRSI38-236)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-236
Lokale Artikelnummer::
PRSI38-236
Beschreibung:
Macrophage Inflammatory Protein 3 alpha is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. It inhibits proliferation of myeloid progenitors in colony formation assays. It binds to CCR6.
Was product number XP-5713-M
VE:
1 * 500 µG
Lieferant:
MP Biomedicals
Beschreibung:
2-Hydroxypropyl-beta-cyclodextrin are non-toxic solubilisers. The solubility of drugs increases linearly with the concentration of 2-Hydroxypropyl-b-cyclodextrin in aqueous buffer. The formation of drug/cyclodextrin complexes is a rapidly reversible reaction and complexes exist both in solution and crystalline states.
Artikel-Nr:
(PRSI91-830)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-830
Lokale Artikelnummer::
PRSI91-830
Beschreibung:
Cytokine are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteine. CCL24 diaplays the chemotactic for resting T-lymphocytes and eosinophils. CCL24 has lower chemotatic activity for neutrophils, none for monocytes and activated lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell lines.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-579)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-579
Lokale Artikelnummer::
PRSI79-579
Beschreibung:
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
VE:
1 * 100 µG
Lieferant:
DIVERSIFIED BIOTECH
Beschreibung:
These Cryo-Tags® polypropylene cryo labels accept printing from direct thermal printers such as Dymo® LabelWriter® to print popular barcode formats for fast easy sample identification.
Artikel-Nr:
(PRSI27-114)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-114
Lokale Artikelnummer::
PRSI27-114
Beschreibung:
TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-184)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-184
Lokale Artikelnummer::
PRSI27-184
Beschreibung:
SLC25A6 catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. SLC25A6 may participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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