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Horizontal+Gel+Electrophoresis+Systems
Artikel-Nr:
(BOSSBS-1009R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1009R-A488
Lokale Artikelnummer::
BOSSBS-1009R-A488
Beschreibung:
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1206R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1206R-FITC
Lokale Artikelnummer::
BOSSBS-1206R-FITC
Beschreibung:
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1206R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1206R-A680
Lokale Artikelnummer::
BOSSBS-1206R-A680
Beschreibung:
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1764R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1764R-CY3
Lokale Artikelnummer::
BOSSBS-1764R-CY3
Beschreibung:
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12577R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12577R-HRP
Lokale Artikelnummer::
BOSSBS-12577R-HRP
Beschreibung:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD, BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity. Also interacts with APAF1, RAF1, TP53BP2, BBC3, BCL2L1 and BNIPL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8604R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8604R-CY3
Lokale Artikelnummer::
BOSSBS-8604R-CY3
Beschreibung:
Major histocompatibility complex (MHC) molecules form an integral part of the immune response system. They are cell-surface receptors that bind peptides and present them to T lymphocytes. Human leukocyte antigens (HLAs) are polymorphic members of the MHC family that are specifically involved in the presentation of antigens to the T cell receptor. There are two classes of HLA antigens: class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Class I molecules are expressed in nearly all cells and play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-B encodes a membrane anchored heavy chain which hetero-dimerizes with a light chain (∫-2-Microglobulin) to form MHC-I. Polymorphisms yield hundreds of HLA-B alleles. The HLA-B27 allele appears with increased frequency in uveitis patients.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12577R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12577R-A488
Lokale Artikelnummer::
BOSSBS-12577R-A488
Beschreibung:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD, BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity. Also interacts with APAF1, RAF1, TP53BP2, BBC3, BCL2L1 and BNIPL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12577R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12577R-FITC
Lokale Artikelnummer::
BOSSBS-12577R-FITC
Beschreibung:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD, BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity. Also interacts with APAF1, RAF1, TP53BP2, BBC3, BCL2L1 and BNIPL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12577R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12577R-A647
Lokale Artikelnummer::
BOSSBS-12577R-A647
Beschreibung:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD, BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity. Also interacts with APAF1, RAF1, TP53BP2, BBC3, BCL2L1 and BNIPL.
VE:
1 * 100 µl
Lieferant:
Avantor Fluid Handling
Beschreibung:
Erleichtert das Pumpen bei niedrigen Flussraten!
Artikel-Nr:
(BOSSBS-0123R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0123R-A488
Lokale Artikelnummer::
BOSSBS-0123R-A488
Beschreibung:
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K >neuromedin-K >substance P.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0123R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0123R-A647
Lokale Artikelnummer::
BOSSBS-0123R-A647
Beschreibung:
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K >neuromedin-K >substance P.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0166R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0166R-A680
Lokale Artikelnummer::
BOSSBS-0166R-A680
Beschreibung:
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
VE:
1 * 100 µl
Artikel-Nr:
(AGLSG5574AA)
Lieferant:
AGILENT
Hersteller-Artikelnummer::
G5574AA
Lokale Artikelnummer::
AGLSG5574AA
Beschreibung:
Hochdurchsatz-(HT)-NGS-Probenvorbereitungsroboter für erhöhte Effizienz und maximale Walkaway-Zeit.
VE:
1 * 1 ST
New Product
Lieferant:
HemaCare
Beschreibung:
CD4+ Helper T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.
Artikel-Nr:
(BOSSBS-4109R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4109R-A750
Lokale Artikelnummer::
BOSSBS-4109R-A750
Beschreibung:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. May play a role in the control of cell migration through the TOR signaling cascade.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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