4-(1,3-Oxazol-5-yl)phenol
Artikel-Nr:
(BOSSBS-11624R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11624R-CY3
Lokale Artikelnummer::
BOSSBS-11624R-CY3
Beschreibung:
Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that leads to the perception of smell. While they share a seven transmembrane domain structure with many neurotransmitter and hormone receptors, olfactory receptors are responsible for the recognition and transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. Both OR2A4 (olfactory receptor 2A4) and OR2A7 (olfactory receptor 2A7) are 310 amino acid multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family. The gene that encodes OR2A4 maps to human chromosome 6q23, while the gene that encodes OR2A7 maps to human chromosome 7q35.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11660R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11660R-CY7
Lokale Artikelnummer::
BOSSBS-11660R-CY7
Beschreibung:
The homeobox is DNA sequence that is approximately 180 base pairs long that is involved in all steps of the developmental regulation of animals, fungi and plants, from embryogenesis to cell differentiation. The homeobox encodes a protein domain of about 60 amino acids, called the homeodomain, that can bind to DNA. The gastrulation brain homeobox 1 (GBX1) gene, along with another homeobox gene (EN2), maps to chromosome 7q36, and is expressed in septal and pallidal areas and in the basal forebrain cholinergic system, an area implicated in Alzheimer’s disease. The GBX1 gene encodes the GBX1 protein, which localizes to the nucleus and contains 1 homeobox DNA-binding domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11339R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11339R-CY5
Lokale Artikelnummer::
BOSSBS-11339R-CY5
Beschreibung:
Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8718R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8718R-CY3
Lokale Artikelnummer::
BOSSBS-8718R-CY3
Beschreibung:
RSAD2 is a 361 amino acid protein that is involved in antiviral defense against pathogens such as Hep C, Cytomegalovirus and HIV-1. Localized to the cytosolic side of the endoplasmic reticulum and relocated to the Golgi apparatus upon viral infection, RSAD2 is thought to prevent viral budding by disrupting lipid rafts at the plasma membrane and supporting the Interferon-induced antiviral state of the cell. Additionally, RSAD2 can bind to and inactivate FDPS (an enzyme that is crucial for the synthesis of cholesterol and geranylated and farnesylated proteins), thereby playing a role in lipid synthesis. Overexpression of RSAD2 leads to abnormal lipid accumulation that is associated with atherosclerosis, a chronic inflammatory disease characterized by hardened arteries.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11339R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11339R-CY7
Lokale Artikelnummer::
BOSSBS-11339R-CY7
Beschreibung:
Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE27137344-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
27137344-25G
Lokale Artikelnummer::
MOLE27137344-25G
Beschreibung:
3-Amino-4-chlorbenzoesäure
VE:
1 * 25 g
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Artikel-Nr:
(BOSSBS-9414R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9414R-A555
Lokale Artikelnummer::
BOSSBS-9414R-A555
Beschreibung:
NET-4, also known as TSPAN5 or TM4SF9, is a 268 amino acid multi-pass membrane protein that belongs to the tetraspanin family and is thought to play a role in signal transduction events related to cell development, activation, growth and motility. The gene encoding NET-4 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5751R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5751R-HRP
Lokale Artikelnummer::
BOSSBS-5751R-HRP
Beschreibung:
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9541R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9541R-A350
Lokale Artikelnummer::
BOSSBS-9541R-A350
Beschreibung:
Orai2 is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins. Localizing to the plasma membrane, Orai2 plays an important role in store-operated calcium (SOC) entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response. Orai2 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11914R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11914R-HRP
Lokale Artikelnummer::
BOSSBS-11914R-HRP
Beschreibung:
Nrarp (NOTCH-regulated ankyrin repeat protein) is a 114 amino acid protein that contains two ANK repeats and is thought to play a role in the formation of somites. The gene encoding Nrarp maps to human chromosome 9, which contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9098R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9098R-A750
Lokale Artikelnummer::
BOSSBS-9098R-A750
Beschreibung:
ANKS3 is a 656 amino acid protein that contain six ANK repeats and one SAM (sterile alpha motif) domain. The gene encoding ANKS3 maps to human chromosome 16. Chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterised by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11841R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11841R-A750
Lokale Artikelnummer::
BOSSBS-11841R-A750
Beschreibung:
TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3000 genes and comprises nearly 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11914R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11914R-FITC
Lokale Artikelnummer::
BOSSBS-11914R-FITC
Beschreibung:
Nrarp (NOTCH-regulated ankyrin repeat protein) is a 114 amino acid protein that contains two ANK repeats and is thought to play a role in the formation of somites. The gene encoding Nrarp maps to human chromosome 9, which contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13697R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13697R-HRP
Lokale Artikelnummer::
BOSSBS-13697R-HRP
Beschreibung:
Transmembrane proteins contain transmembrane domains that are usually characterized by alpha-helical structures. Transmembrane proteins exist as thermodynamically stable hetero- and homodimers that interact with the lipid bilayer and are involved in both material exchange and communication between the cell and the environment. PL6 is a 351 amino acid multi-pass membrane protein that is highly expressed in kidney and skeletal muscle with lower levels of expression detected in liver, placenta, prancreas, lung, heart and brain. PL6 contains one phosphoserine residue and several transmembrane domains, suggesting that it may participate in protein exchange and signaling events between cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11914R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11914R-A647
Lokale Artikelnummer::
BOSSBS-11914R-A647
Beschreibung:
Nrarp (NOTCH-regulated ankyrin repeat protein) is a 114 amino acid protein that contains two ANK repeats and is thought to play a role in the formation of somites. The gene encoding Nrarp maps to human chromosome 9, which contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12357R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12357R-A350
Lokale Artikelnummer::
BOSSBS-12357R-A350
Beschreibung:
CFDP1 is a 299 amino acid protein that is involved in embryogenesis and normal cell function. When treated with CFDP1 peptide, mouse molar teeth increase in size, whereas treating cells with against CFDP1 shows an increase in the number of apoptotic cells and gradual tooth disintegration. CFDP1 is highly expressed in developing mouse teeth and is expressed at lower levels in liver, lung and heart. The gene encoding CFDP1 maps to human chromsome 16, in a region that has been associated with inherited craniofacial diseases, such as fanconi anemia type A. There are two isoforms of CFDP1 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
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