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3-(Chlorsulfonyl)benzoesäure
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Artikel-Nr:
(BLDPBD00805493-100)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD00805493-100
Lokale Artikelnummer::
BLDPBD00805493-100
Beschreibung:
(S)-1-Amino-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol hydrochloride 95%
VE:
1 * 100 mg
Artikel-Nr:
(8.15046.0001)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.15046.0001
Lokale Artikelnummer::
MERC8.15046.0001
Beschreibung:
2-Propanol-[D7]
VE:
1 * 1 mL
Lieferant:
Thermo Scientific
Beschreibung:
4'-Nonylacetophenon
Lieferant:
FLUOROCHEM
Beschreibung:
1-(3-Fluorphenyl)imidazol
Lieferant:
Merck
Beschreibung:
2-Propanol Referenzstandard zum Analysieren von Tabak, Supelco®
Lieferant:
Merck
Beschreibung:
Dimercaprol zur Synthese, Sigma-Aldrich®
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-(Bicyclo[2.2.1]hept-5-en-2-yl)-1,1,1-trifluoro-2-(trifluoromethyl)propan-2-ol 97%
Lieferant:
Alfa Aesar
Beschreibung:
N,N,N',N'-Tetramethylethylendiamin (TEMED) 99%
Artikel-Nr:
(BOSSBS-2803R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2803R-A350
Lokale Artikelnummer::
BOSSBS-2803R-A350
Beschreibung:
Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2803R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2803R-A555
Lokale Artikelnummer::
BOSSBS-2803R-A555
Beschreibung:
Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2803R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2803R-A647
Lokale Artikelnummer::
BOSSBS-2803R-A647
Beschreibung:
Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death.
VE:
1 * 100 µl
Artikel-Nr:
(8.14513.0025)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.14513.0025
Lokale Artikelnummer::
MERC8.14513.0025
Beschreibung:
1-Chlor-3-methoxy-2-propanol, Sigma-Aldrich®
VE:
1 * 25 mL
Artikel-Nr:
(8.22263.2500)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.22263.2500
Lokale Artikelnummer::
MERC8.22263.2500
Beschreibung:
(±)-2-Butanol, EMPLURA®, Supelco®
VE:
1 * 2,5 L
Lieferant:
Sigma-Aldrich
Beschreibung:
N,N,N',N'-Tetramethylethylendiamin (TEMED), Sigma-Aldrich®
Artikel-Nr:
(20308.156)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC20308.156
Beschreibung:
EGTA (Ethylenglycolbis(2-aminoethylether)-N,N,N',N'-tetraessigsäure) ≥98,5% analytisches Reagens
VE:
1 * 50 g
Artikel-Nr:
(FLUO018331-10G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
018331-10G
Lokale Artikelnummer::
FLUO018331-10G
Beschreibung:
4'-Butylacetophenon
VE:
1 * 10 g
 This is a MarketSource item. Additional charges may apply
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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