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K+LINE+LOGISTIS+(USA)+INC
Artikel-Nr:
(BOSSBS-7745R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7745R-A647
Lokale Artikelnummer::
BOSSBS-7745R-A647
Beschreibung:
Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner.Tissue specificity: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(PRSIXPS-2013)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XPS-2013
Lokale Artikelnummer::
PRSIXPS-2013
Beschreibung:
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-6114R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6114R-CY5.5
Lokale Artikelnummer::
BOSSBS-6114R-CY5.5
Beschreibung:
This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7513R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7513R-FITC
Lokale Artikelnummer::
BOSSBS-7513R-FITC
Beschreibung:
BAI 1 protein is likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. It may function in cell adhesion and signal transduction in the brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5957R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5957R-CY7
Lokale Artikelnummer::
BOSSBS-5957R-CY7
Beschreibung:
Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI2497)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2497
Lokale Artikelnummer::
PRSI2497
Beschreibung:
IL-22 Receptor Antibody: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI90-394)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-394
Lokale Artikelnummer::
PRSI90-394
Beschreibung:
CD40 is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 contains 4 cysteine-rich repeats in the extracellular domain and is expressed in B cells, dendritic cells, macrophages, endothelial cells and several tumour cell lines. The cognate interaction between CD40 and CD40 ligand (CD154) on T cells activates NF-kappaB, Jun N-terminal kinase and Janus kinase signal transducers and activators of transcription pathways. Several different TRAF proteins (adapter proteins) have been identified to serve as mediators of the signal transduction. In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation and thus is thought to be an early event in Alzheimer disease pathogenesis. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3), an autosomal recessive disorder characterised by the inability of B cells to undergo isotype switching, as well as an inability to mount an antibody-specific immune response and a lack of germinal center formation.
VE:
1 * 100 µG
Lieferant:
Hichrom Limited
Beschreibung:
In-Line Filter, Avantor® Hichrom, VE: 5
Artikel-Nr:
(BOSSBS-6238R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6238R-A680
Lokale Artikelnummer::
BOSSBS-6238R-A680
Beschreibung:
Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1620R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1620R-HRP
Lokale Artikelnummer::
BOSSBS-1620R-HRP
Beschreibung:
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6238R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6238R-A350
Lokale Artikelnummer::
BOSSBS-6238R-A350
Beschreibung:
Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2483R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2483R-A555
Lokale Artikelnummer::
BOSSBS-2483R-A555
Beschreibung:
Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10153R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10153R-CY5
Lokale Artikelnummer::
BOSSBS-10153R-CY5
Beschreibung:
Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts.Belongs to the SECTM family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4221R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4221R
Lokale Artikelnummer::
BOSSBS-4221R
Beschreibung:
Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0823R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0823R-CY5
Lokale Artikelnummer::
BOSSBS-0823R-CY5
Beschreibung:
Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6746R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6746R-HRP
Lokale Artikelnummer::
BOSSBS-6746R-HRP
Beschreibung:
TULP2 is a member of a family of tubby-like (TULP) proteins which share a conserved C terminal region of approximately 200 amino acid residues. It is strongly expressed in testis and is expressed in the retina. It is also expressed in cancer cell lines.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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