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Artikel-Nr:
(NUCKGLC-411.0001)
Lieferant:
NU-CHEK-PREP
Hersteller-Artikelnummer::
GLC-411.0001
Lokale Artikelnummer::
NUCKGLC-411.0001
Beschreibung:
γ-Linolensäuremethylester
VE:
1 * 1 ST
 This is a MarketSource item. Additional charges may apply
Lieferant:
MP Biomedicals
Beschreibung:
Soluble in water (100 mg/ml - clear, colorless solution).
Artikel-Nr:
(PRSI90-541)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-541
Lokale Artikelnummer::
PRSI90-541
Beschreibung:
Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilisaion of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerisaion and signalling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-252)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-252
Lokale Artikelnummer::
PRSI91-252
Beschreibung:
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is translocated from the mitochondria to the nucleus to function as a proapoptotic factor in a caspase-independent pathway, while in normal mitochondria, it functions as an antiapoptotic factor via its oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces parthanatos i.e., caspase-independent fragmentation of chromosomal DNA. AIFM1 interacts with EIF3G, and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. It binds to DNA in a sequence-independent manner and plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
Phenol, Kristalle, Sigma-Aldrich®
Artikel-Nr:
(PRSI33-990)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-990
Lokale Artikelnummer::
PRSI33-990
Beschreibung:
Transforming growth factor alpha is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal growth factor (EGF) family, TGFa is a mitogenic polypeptide. The protein becomes activated when binding to receptors capable of protein kinase activity for cellular signaling. TGFa is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. [Wiki].
VE:
1 * 100 µG
Artikel-Nr:
(PRSI48-376)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-376
Lokale Artikelnummer::
PRSI48-376
Beschreibung:
Soluble Epoxide Hydrolase (sEH) also known as cytosolic Epoxide Hydrolase is a phase I xenobiotic-metabolizing enzyme that converts epoxyeicosatrienoic acids (EETs) into their corresponding dihydroxyeicosatrienoic acids (DHETs). EETs are thought to be involved in vascular tone, ion channel regulation, mitogenesis and cell signaling. DHETs have, in general, less biological activity then EETs and are more readily excreted, thus hydration of EETs by sEH maybe a means of attenuating or eliminating their activity.sEHs have been identified in many tissues including liver, kidney, adrenal, pancreatic islets, gi tract and vascular smooth muscle.
VE:
1 * 50 µG
Lieferant:
Avantor
Beschreibung:
Crystals. Lot analysis on label.
Artikel-Nr:
(PRSI2099)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2099
Lokale Artikelnummer::
PRSI2099
Beschreibung:
CX3CL1 Antibody: Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-alpha in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-444)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-444
Lokale Artikelnummer::
PRSI25-444
Beschreibung:
RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-484)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-484
Lokale Artikelnummer::
PRSI92-484
Beschreibung:
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.
VE:
1 * 50 µG
Artikel-Nr:
(PIER89802)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
89802
Lokale Artikelnummer::
PIER89802
Beschreibung:
The I-PER Insect Cell Protein Extraction Reagent enables gentle and effective extraction of soluble protein from baculovirus-infected insect cells grown in suspension or monolayer culture. The baculovirus insect cell expression system is an efficient and popular system for production of recombinant (eukaryotic) proteins in cell culture. Proteins expressed in baculoviral systems can be used for structural analyses, biochemical assays and a variety of other applications. I-PER Reagent maintains functionality of extracted proteins and is directly compatible with downstream applications such as protein assays, Western blotting and 6xHis-tagged protein purification.
VE:
1 * 250 mL
Artikel-Nr:
(PRSI77-034)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-034
Lokale Artikelnummer::
PRSI77-034
Beschreibung:
The NIB42 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. The NIB42 antibody neutralizes IFN-gamma.
VE:
1 * 25 Tests
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-IFN-gamma R beta chain Armenian hamster Monoclonal Antibody [clone: MOB-47] (APC (Allophycocyanin))
Artikel-Nr:
(BOSSBS-11773R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11773R-A750
Lokale Artikelnummer::
BOSSBS-11773R-A750
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyse the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilisation, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyses the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11992R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11992R-A555
Lokale Artikelnummer::
BOSSBS-11992R-A555
Beschreibung:
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A Alpha and PP2A Beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-Alpha and -A-Beta, PP2A-B-Alpha and -B-Beta, PP2A-C-Alpha and -C-Beta, PP2A-B56-Alpha, -B56-Beta, -B56-gamma and -B56-Delta.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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