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Chromon-2-carbons\\u00E4ure
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Chromon-2-carbons\\u00E4ure
Lieferant:
Thermo Scientific
Beschreibung:
Für die Kultivierung der meisten Zelltypen, ohne Matrixbeschichtung. Die Membranen wurden mit der oberen Polystyrolstruktur verschweißt. Die Polycarbonat-Membran besitzt größere Poren und eignet sich für viele Zellkulturanwendungen, wie z. B. für Transportstudien, Toxizitätstests, Chemotaxis-Studien und die Elektronenmikroskopie. Beide Membranarten sind in nassem Zustand transparent und für die Verwendung mit Phasenkontrast- und optischen Systemen nach Normanski tauglich.
Lieferant:
CHIRAL TECHNOLOGIES
Beschreibung:
Zur Trennung von sauren chiralen Verbindungen mit Carboxyl-, Phosphon-, Phosphin- Phosphor- oder Sulfonsäuregruppen. In einigen Fällen können auch schwach saure Verbindungen wie Phenole getrennt werden.
Lieferant:
Alfa Aesar
Beschreibung:
2-Propanol ≥99,7% für die Gaschromatographie
Lieferant:
Merck
Beschreibung:
With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.
Lieferant:
VARIAN
Beschreibung:
Bond Elut™ PRS is a strong cation exchange sorbent that is also relatively high in polarity. With no appreciable degree of hydrophobicity, in non-polar solvents, PRS is capable of polar and hydrogen bonding interactions. Due to the very low pKa of PRS, a high ionic strength eluent must be used, and so the use of PRS is recommended for weaker cationic species such as pyridinium compounds.
Artikel-Nr:
(PRSI30-425)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-425
Lokale Artikelnummer::
PRSI30-425
Beschreibung:
TYMS catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-47 CR601528.1 1-47 48-1099 X02308.1 14-1065 1100-1603 BC083512.1 1067-1570
VE:
1 * 50 µG
Artikel-Nr:
(HONC65748-200L-RC)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
65748-200L-RC
Lokale Artikelnummer::
HONC65748-200L-RC
Beschreibung:
Petroleumbenzin, 40-60°C für die Gaschromatographie, Burdick & Jackson™
VE:
1 * 200 L
Artikel-Nr:
(3043-25)
Lieferant:
MACRON AVANTOR BRAND
Lokale Artikelnummer::
MACR3043-25
Beschreibung:
ChromAR®—Solvents that meet ACS specifications and are suitable for liquid chromatography and UV-spectrophotometry.
VE:
1 * 2,5 L
Lieferant:
VARIAN
Beschreibung:
Bond Elut™ Diol (2OH) resembles unbonded silica in its tendency for strong hydrogen bonding with analytes. 2OH can also be employed in the non-polar mode because the hydrocarbon spacer on its functional group provides enough non-polar character for retention of hydrophobic analytes. Bond Elut™ Diol is a listed SPE device for the DIN 14333-1 method on benzimidazole fungicides.
Lieferant:
VARIAN
Beschreibung:
The Bond Elut™ Certify extraction cartridge utilises a packed bed consisting of a special, non-polar C8 sorbent and a strong cation exchanger (SCX). Certify is most commonly used to extract basic (cationic) drugs from urine and blood, but it is also very effective for extraction of a wide range of compounds from a diverse range of aqueous matrices.
Artikel-Nr:
(PRSI33-854)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-854
Lokale Artikelnummer::
PRSI33-854
Beschreibung:
This antibody is specific to a conserved determinant of the p53 protein. PAb 122 binds to the C-terminus (aa 370-378) of both wild type and mutated p53. When microinjected into nuclei, PAb 122 blocked re-entry into the S-phase of the cell cycle. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. p53 binds to a DNA consensus sequence, the p53 response element, and it regulates normal cell growth cycle events by activating transcription of genes, involved either in progression through the cycle, or causing arrest in G1 when the genome is damaged. In most transformed and tumor cells the concentration of p53 is increased 5-1000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). The protein in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Its the most commonly mutated gene in spontaneously occurring human cancers. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation.
VE:
1 * 100 µG
Lieferant:
VARIAN
Beschreibung:
PBA is a unique sorbent consisting of a phenylboronic acid covalently linked to a silica gel surface. Covalent processes result in a higher retention to the sorbent surface than other mechanisms, resulting in superior clean-up. The boronate group has a high specificity for cis-diol containing compounds such as catechols, nucleic acids, low molecular weight proteins and carbohydrates.
Lieferant:
Agilent
Beschreibung:
Poroshell 300 columns are ideal for fast separations of proteins and peptides because the superficially porous particle allows for fast flow rates to be used while maintaining sharp, efficient peaks. Peptides and proteins are typically separated slowly to reduce the potential peak broadening of these slow diffusing analytes. However, Poroshell columns use a superficially porous particle made with a thin layer of porous silica on a solid core of silica, reducing the diffusion distance for proteins making practical rapid HPLC separations of peptides and proteins up to 500 to 1000 kDa.
Artikel-Nr:
(5398-25)
Lieferant:
MACRON AVANTOR BRAND
Lokale Artikelnummer::
MACR5398-25
Beschreibung:
tert-Butylmethylether ≥99,0% (durch GC, auf Wasserinhalt korrigiert), ChromAR® für die Flüssigchromatographie, für die UV-Spektrophotometrie, Macron Fine Chemicals™
VE:
1 * 2,5 L
Artikel-Nr:
(PRSI79-871)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-871
Lokale Artikelnummer::
PRSI79-871
Beschreibung:
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes. Can activate distinct gene expression programs in macrophages and can induce significant apoptosis in primary macrophages.
VE:
1 * 100 µG
Lieferant:
ATLAS - the shoe company
Beschreibung:
Das textile Sportline-Obermaterial dieses ESD-Sicherheitsschuhs ist wasserabweisend, schnelltrocknend und widerstandsfähig. Das ganzheitliche INNOFLEX Laufsohlensystem unterstützt den Läufer in jeder Phase der Bewegung.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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