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N-Cyano-N\\\',S-Dimethylisothiohernstoff
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N-Cyano-N\\\',S-Dimethylisothiohernstoff
Artikel-Nr:
(BOSSBS-10221R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10221R-A350
Lokale Artikelnummer::
BOSSBS-10221R-A350
Beschreibung:
Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11542R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11542R
Lokale Artikelnummer::
BOSSBS-11542R
Beschreibung:
Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.
VE:
1 * 100 µl
Artikel-Nr:
(QEDB11505)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
11505
Lokale Artikelnummer::
QEDB11505
Beschreibung:
Anti-Cav3.2 Ca+2 Channel Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(QEDB11565)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
11565
Lokale Artikelnummer::
QEDB11565
Beschreibung:
Anti-Cav3.1 Ca+2 Channel Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-12049R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12049R-FITC
Lokale Artikelnummer::
BOSSBS-12049R-FITC
Beschreibung:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12049R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12049R-A350
Lokale Artikelnummer::
BOSSBS-12049R-A350
Beschreibung:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1056R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1056R-A350
Lokale Artikelnummer::
BOSSBS-1056R-A350
Beschreibung:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12049R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12049R-A647
Lokale Artikelnummer::
BOSSBS-12049R-A647
Beschreibung:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
VE:
1 * 100 µl
Artikel-Nr:
(USBIA1475-08E3)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A1475-08E3
Lokale Artikelnummer::
USBIA1475-08E3
Beschreibung:
Anti-AMPK1, 2 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(USBI044379)
Lieferant:
US Biological
Hersteller-Artikelnummer::
044379
Lokale Artikelnummer::
USBI044379
Beschreibung:
Anti-CHAMP1 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI145997)
Lieferant:
US Biological
Hersteller-Artikelnummer::
145997
Lokale Artikelnummer::
USBI145997
Beschreibung:
Anti-CASP14 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBI033218)
Lieferant:
US Biological
Hersteller-Artikelnummer::
033218
Lokale Artikelnummer::
USBI033218
Beschreibung:
Anti-CASP3 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBIC2069-40L1)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C2069-40L1
Lokale Artikelnummer::
USBIC2069-40L1
Beschreibung:
Anti-CTNNA1 Goat polyclonal antibody
VE:
1 * 50 µG
Artikel-Nr:
(UVEX9400.517)
Lieferant:
UVEX
Hersteller-Artikelnummer::
9400.517
Lokale Artikelnummer::
UVEX9400.517
Beschreibung:
Ersatzscheibe, CA farblos, beschlagfrei, Farbe (Linse): Klar, Beschlagschutz: +
VE:
1 * 10 ST
Artikel-Nr:
(BOSSBS-11644R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11644R-A750
Lokale Artikelnummer::
BOSSBS-11644R-A750
Beschreibung:
Members of the calsyntenin protein family are localised to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-1, also known as CSTN1, PIK3CD, Alzheimer-related cadherin-like protein, non-classical cadherin XB31alpha, KIAA0911, ALC-ALPHA, alcalpha1, alcalpha2 or FLJ32258, is a 981 amino acid single-pass type I membrane protein that localizes to the membrane of endoplasmic reticulum, Golgi apparatus, cell projections and postsynaptic cells. Expressed in brain, calsyntenin-1 is also found at lower levels in placenta, skeletal muscle, heart and kidney. Calsyntenin-1 binds synaptic Ca²⁺ with its cytoplasmic domain and plays a role in extracellular proteolysis. Calsyntenin-1 is also known to form a complex with X11 Beta and APP to suppress the metabolic cleavage of APP, and docks vesicular cargo to KLC1. Calsyntenin-1 may be related to the development or progression of Alzheimer's disease, and two calsyntenin-1 isoforms are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1205R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1205R-A350
Lokale Artikelnummer::
BOSSBS-1205R-A350
Beschreibung:
Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP3, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p9RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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