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Methyl+trans-3-hydroxycyclobutanecarboxylate
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Methyl+trans-3-hydroxycyclobutanecarboxylate
Artikel-Nr:
(BOSSBS-13343R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-FITC
Lokale Artikelnummer::
BOSSBS-13343R-FITC
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(REST30274)
Lieferant:
Restek
Hersteller-Artikelnummer::
30274
Lokale Artikelnummer::
REST30274
Beschreibung:
Prepared from an equal-volume blend of 5W30, 10W30, 10W40, and 20W50 motor oils. After blending, a precisely weighed amount of the composite is added to a volumetric flask to produce the standard.
Motor Oil standards may exhibit lot-to-lot variation.
VE:
1 * 1 mL
Lieferant:
Sigma-Aldrich
Beschreibung:
Fumarsäuredinitril, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Tiglinsäure, Sigma-Aldrich®
Lieferant:
MP Biomedicals
Beschreibung:
Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that mediates the functions of vitamin A required for growth and development. It affects gene transcription and modulates a wide variety of biological processes like Cell Proliferation, Differentiation, including Apoptosis. Retinoic Acid mediated gene transcription depends on the rate of transport of Retinoic Acid to target cells and the timing of exposure of Retinoic Acid to RARs (Retinoic Acid Receptors) in the target tissues
Artikel-Nr:
(SPCMP1408-125GM)
Lieferant:
Spectrum Chemical
Hersteller-Artikelnummer::
P1408-125GM
Lokale Artikelnummer::
SPCMP1408-125GM
Beschreibung:
Potassium Sorbate, Powder, FCC is used as an antimicrobial preservative. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage, nutritional supplement and personal care applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
VE:
1 * 125 g
Artikel-Nr:
(554325-25)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
554325-25
Lokale Artikelnummer::
CALB554325-25
Beschreibung:
Resveratrol, Millipore®
VE:
1 * 25 mg
Lieferant:
Biotium
Beschreibung:
This MAb recognizes an antigen associated with the Golgi complex in human cells only. It can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae.
Artikel-Nr:
(BOSSBS-9201R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9201R-CY3
Lokale Artikelnummer::
BOSSBS-9201R-CY3
Beschreibung:
IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7736R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7736R-CY3
Lokale Artikelnummer::
BOSSBS-7736R-CY3
Beschreibung:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-HRP
Lokale Artikelnummer::
BOSSBS-13343R-HRP
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(SIALR3375-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
R3375-1G
Lokale Artikelnummer::
SIALR3375-1G
Beschreibung:
O15-Palmitoylretinol, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(BSENR-167-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-167-100
Lokale Artikelnummer::
BSENR-167-100
Beschreibung:
FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. SUBUNIT: Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma1/AP1G1 or gamma2/AP1G2 and beta1A/AP1B1 or beta1B/AP1B1), a medium adaptin (mu1A/AP1M1 or mu1B/AP1M2) and a small adaptin (sigma1A/AP1S1 or sigma1B/AP1S2 or sigma1C/AP1S3). SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasmic vesicle; cytoplasmic vesicle membrane; peripheral membrane protein; cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Widely expressed. DISEASE: Deletion of the AP1B1 gene may play a role in the tumorigenesis of meningiomas. SIMILARITY: Belongs to the adaptor complexes large subunit family.
VE:
1 * 100 µl
Artikel-Nr:
(USBI151114)
Lieferant:
US Biological
Hersteller-Artikelnummer::
151114
Lokale Artikelnummer::
USBI151114
Beschreibung:
Anti-TMX1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(REST32034)
Lieferant:
Restek
Hersteller-Artikelnummer::
32034
Lokale Artikelnummer::
REST32034
Beschreibung:
Organic Standard, Pesticide standard mix B includes aldrin, 4,4'-DDD, 4,4'-DDE, α-BHC, β-BHC, γ-BHC, endosulfan sulfate, cis-chlordane, endrin ketone, trans-chlordane, in hexane, 1 ml/ampoule
VE:
1 * 1 mL
Artikel-Nr:
(USBI042683-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042683-BIOTIN
Lokale Artikelnummer::
USBI042683-BIOTIN
Beschreibung:
Anti-TCEA3 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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