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Methyl+2,2,2-trimethoxyacetate
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Methyl+2,2,2-trimethoxyacetate
Lieferant:
Alfa Aesar
Beschreibung:
Boc-Asp-OMe 98%
Artikel-Nr:
(BWRLBS7241)
Lieferant:
Bioworld Technology
Hersteller-Artikelnummer::
BS7241
Lokale Artikelnummer::
BWRLBS7241
Beschreibung:
Synthetic peptide conjugated to KLH derived from within residues 1-100 of Human Histone H3, di methylated at K79.
VE:
1 * 100 µG
Lieferant:
Alfa Aesar
Beschreibung:
Methylviolett 0,1% (w/v) in wässriger Lösung
Lieferant:
Alfa Aesar
Beschreibung:
6-Nitro-m-kresol ≥97%
Artikel-Nr:
(374776-5G)
Lieferant:
SIGMA ALDRICH MICROSCOPY
Hersteller-Artikelnummer::
374776-5G
Lokale Artikelnummer::
SIAM374776-5G
Beschreibung:
4-Methoxybiphenyl has been used as a standard reagent whose fluorescence intensity is associated with the fluorescence characteristics of the products of derivatisation reaction for aryl halides with phenylboronic acid (PBA).
VE:
1 * 5 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Amino-5-nitro-6-picolin
Artikel-Nr:
(APOSOR0108-500G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR0108-500G
Lokale Artikelnummer::
APOSOR0108-500G
Beschreibung:
5-Nitro-o-kresol 98%
VE:
1 * 500 g
Artikel-Nr:
(BOSSBS-5915R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R-A555
Lokale Artikelnummer::
BOSSBS-5915R-A555
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5915R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R-A647
Lokale Artikelnummer::
BOSSBS-5915R-A647
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0301R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0301R-A680
Lokale Artikelnummer::
BOSSBS-0301R-A680
Beschreibung:
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0301R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0301R-A647
Lokale Artikelnummer::
BOSSBS-0301R-A647
Beschreibung:
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.
VE:
1 * 100 µl
Artikel-Nr:
(8.18094.0010)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.18094.0010
Lokale Artikelnummer::
MERC8.18094.0010
Beschreibung:
(1,3-Dioxolan-2-ylmethyl)triphenylphosphoniumbromid zur Synthese, Sigma-Aldrich®
VE:
1 * 10 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(2-Fluorphenyl)methylsulfon
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-Fluor-4-(methylsulfonyl)-2-nitrobenzol
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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