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Methyl-6-amino-5-brompicolinat
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Methyl-6-amino-5-brompicolinat
Lieferant:
COMBI-BLOCKS
Beschreibung:
Methyl-3-(Boc-amino)picolinat
Lieferant:
FLUOROCHEM
Beschreibung:
5-Amino-3-methyl-1,2,4-thiadiazol
Artikel-Nr:
(BOSSBS-11113R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11113R-CY5
Lokale Artikelnummer::
BOSSBS-11113R-CY5
Beschreibung:
As a subfamily of the cadherin superfamily, protocadherins are cadherin-like cell adhesion proteins that contain up to seven extracellular domains and are predominantly expressed in the nervous system. Importantly, the adhesion mechanism of protocadherins is distinct from classic cadherins. Through inactivation or overexpression, several protocadherins have been implicated in a variety of cancers. Protocadherin-20 (PCDH20), also known as protocadherin-13, is a 924 amino acid protein containing 6 cadherin domains and potentially functioning as a calcium-dependent cell-adhesion protein. In non-small cell lung cancer cell lines, a homozygous loss of PCDH20 was identified through either deletion of one allele and methylation of the other or methylation of both alleles. Hypermethylation of PCDH20 is associated with worse prognosis and clinical outcome, suggesting that PCDH20 may function as a tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12198R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12198R
Lokale Artikelnummer::
BOSSBS-12198R
Beschreibung:
JMJD2B is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure; the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, JMJD2C and JMJD2D. JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate. JMJD2B is a ubiquitously expressed nuclear protein.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
Methyl-2-amino-4,5-dimethoxybenzoat
Artikel-Nr:
(BOSSBS-9509R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9509R-A750
Lokale Artikelnummer::
BOSSBS-9509R-A750
Beschreibung:
Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene encoding LRRC3B is a tumour suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD91315-100G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD91315-100G
Lokale Artikelnummer::
BLDPBD91315-100G
Beschreibung:
4-({[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}methyl)benzoesäure 97%
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-11633R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11633R-A750
Lokale Artikelnummer::
BOSSBS-11633R-A750
Beschreibung:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11632R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11632R-CY7
Lokale Artikelnummer::
BOSSBS-11632R-CY7
Beschreibung:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0930R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0930R-A680
Lokale Artikelnummer::
BOSSBS-0930R-A680
Beschreibung:
HP1 alpha is a component of heterochromatin. It recognises and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11632R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11632R-A647
Lokale Artikelnummer::
BOSSBS-11632R-A647
Beschreibung:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9671R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9671R-HRP
Lokale Artikelnummer::
BOSSBS-9671R-HRP
Beschreibung:
ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9671R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9671R-CY7
Lokale Artikelnummer::
BOSSBS-9671R-CY7
Beschreibung:
ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11632R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11632R-HRP
Lokale Artikelnummer::
BOSSBS-11632R-HRP
Beschreibung:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1800R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1800R-CY5
Lokale Artikelnummer::
BOSSBS-1800R-CY5
Beschreibung:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1800R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1800R-CY3
Lokale Artikelnummer::
BOSSBS-1800R-CY3
Beschreibung:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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