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5-(Methylsulphonyl)-1H-indazole


149 435  results were found

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N'-[1-Cyclopropylaminopropylidene]hydrazinecarboxylic+acid-tert-butyl+ester
 
 
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Lieferant:  Sigma-Aldrich
Beschreibung:   Ethyldiethoxyacetat, Sigma-Aldrich®
Artikel-Nr: (FLUO002978-25G)

Lieferant:  FLUOROCHEM
Hersteller-Artikelnummer:: 002978-25G
Lokale Artikelnummer:: FLUO002978-25G
Beschreibung:   Methyl(methylthio)acetat
VE:  1 * 25 g
Market Source Item This is a MarketSource item. Additional charges may apply
Lieferant:  Cytiva
Beschreibung:   CyDye™ Mono-Reactive Maleimide Fluorescent Dyes are intensely fluorescent and highly water soluble, providing significant advantages over other existing fluorophores.
Lieferant:  Sigma-Aldrich
Beschreibung:   1-Boc-4-piperidon, Sigma-Aldrich®

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 6657
Lokale Artikelnummer:: PRSI6657
Beschreibung:   JMJD3 Antibody: The Jumonji domain-containing protein 3 (JMJD3) functions as a trimethylation-specific demethylase, converting the trimethylated histone H3 Lys27 residue to the dimethylated form, and is thought to also function as a transcriptional repressor. JMJD3 plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. JMJD3 can also interact with and demethylate p53, resulting in its stabilization and localization to the nucleus in mouse embryo fibroblasts during neural stem cell differentiation.
VE:  1 * 100 µG

Lieferant:  Merck Millipore (Oncogene)
Hersteller-Artikelnummer:: 487663-10
Lokale Artikelnummer:: ONCO487663-10
Beschreibung:   4-Nitrophenylphosphat, Sigma-Aldrich®
VE:  1 * 10 mL
Artikel-Nr: (SIAL295795-5G)

Lieferant:  Sigma-Aldrich
Hersteller-Artikelnummer:: 295795-5G
Lokale Artikelnummer:: SIAL295795-5G
Beschreibung:   Ethylbromdifluoracetat, Sigma-Aldrich®
VE:  1 * 5 g
Lieferant:  Restek
Beschreibung:   Diese MXT-5-Säulen bestehen aus mit Siltek behandeltem Edelstahl mit einer Phase mit niedriger Polarität und einer stationären Diphenyl-Dimethylpolysiloxan-Phase mit Kreuzbindung. Alle restlichen Katalysatoren und Fragmente mit niedrigem Molekulargewicht werden aus dem MXT-5-Polymer entfernt, was zu einer engen monomodalen Verteilung und extrem geringem Ausbluten führt.
Lieferant:  GE Healthcare - Whatman
Beschreibung:   These mixed cellulose ester membrane filters are designed for asbestos sampling using the membrane filter method for phase contrast microscopy. Asbestos sampling isolates these fibres from circulating air to determine concentrations.

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 30-787
Lokale Artikelnummer:: PRSI30-787
Beschreibung:   CHN1 contains 1 phorbol-ester/DAG-type zinc finger, 1 Rho-GAP domain and 1 SH2 domain. CHN1 is a GTPase-activating protein for p21-rac and a phorbol ester receptor. It may play an important role in neuronal signal-transduction mechanisms.
VE:  1 * 50 µG
Lieferant:  COMBI-BLOCKS
Beschreibung:   1-Boc-4-piperidon

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 79-827
Lokale Artikelnummer:: PRSI79-827
Beschreibung:   Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
VE:  1 * 100 µG
Artikel-Nr: (BOSSBS-1862R)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-1862R
Lokale Artikelnummer:: BOSSBS-1862R
Beschreibung:   The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. In addition, fibronectin like repeats, a hinge region, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, gelatinase, stomelysin and membrane type MMP subfamilies. All MMPs are synthesized as proenzymes, and most of them are secreted from the cells as proenzymes. Thus, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown. MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer's, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.MMP17 has been reported to be elevated in several tumor cell lines, and is constituitively produced by some normal cell lines. Treatment of cells with Concanavolin A or the phorbol ester TPA stimulates production of MMP17 in some cell types, and the enzyme can be recovered in cell lysates. Shed forms of MMP17 have also been reported.
VE:  1 * 100 µl
Artikel-Nr: (EHERC10016000)

Lieferant:  EHRENSTORFER
Hersteller-Artikelnummer:: C10016000
Lokale Artikelnummer:: EHERC10016000
Beschreibung:   2-Ethoxyethylacetat
VE:  1 * 1 mL
Lieferant:  Sigma-Aldrich
Hersteller-Artikelnummer:: 803642-50MG
Lokale Artikelnummer:: SIAL803642-50MG
Beschreibung:   The amine-reactive portion of SPDP reagents is the N-hydroxysuccinimide (NHS) ester. Reactions are most commonly performed in phosphate, carbonate/bicarbonate, or borate buffers at pH 7-8. Other buffers can be used provided they do not contain primary amines (or thiols or disulfide reducing reagents – see discussion of the sulfhydryl reactivity). The rate of reaction and degradation by hydrolysis increases with increasing pH; for example, the half-life of the NHS ester is several hours at pH 7 and less than 10 minutes at pH 9. NHS-ester reagents like SPDP and LC-SPDP have limited aqueous solubility and must be dissolved in organic solvent before adding them to a reaction mixture. Sulfo-NHS-ester reagents like Sulfo-LC-SPDP are water-soluble and can be added directly to aqueous reaction mixtures.
VE:  1 * 50 mg
Lieferant:  FLUOROCHEM
Beschreibung:   1-Boc-4-piperidon
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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