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(S)-2-Amino-2-(3-chlorophenyl)ethanol
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(S)-2-Amino-2-(3-chlorophenyl)ethanol
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Artikel-Nr:
(BOSSBS-8345R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-CY3
Lokale Artikelnummer::
BOSSBS-8345R-CY3
Beschreibung:
FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0945R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0945R-CY5.5
Lokale Artikelnummer::
BOSSBS-0945R-CY5.5
Beschreibung:
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12071R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12071R-CY7
Lokale Artikelnummer::
BOSSBS-12071R-CY7
Beschreibung:
P2Y purinoceptor 11 (P2Y11) is a 374 amino acid protein belonging to the G-protein coupled receptor one family. P2Y11 is a multi-pass cell membrane protein that acts as a receptor for both ATP and ATD coupled to G proteins. Due to these interactions, P2Y11 is involved in phosphatidylinositol-calcium and adenylyl cyclase pathways. Induced by DMSO and retinoic acid, P2Y11 is highly expressed in spleen tissue. A putative trans-splicing event involving the gene that encodes P2Y11 and an upstream gene encoding PPAN has been found to result in a fusion protein, designated PPAN-P2RY11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13325R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13325R-CY7
Lokale Artikelnummer::
BOSSBS-13325R-CY7
Beschreibung:
GDE4 is a 314 amino acid cytoplasmic and multi-pass membrane protein that belongs to the glycerophosphoryl diester phosphodiesterase family. Expressed in small intestine, placenta, kidney, ovary, thymus, pancreas, spleen, liver and peripheral blood leukocytes, GDE4 contains one GDPD domain and exists as three alternatively spliced isoforms. GDE4 is encoded by a gene that maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1394R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1394R-CY3
Lokale Artikelnummer::
BOSSBS-1394R-CY3
Beschreibung:
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0400R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0400R-CY3
Lokale Artikelnummer::
BOSSBS-0400R-CY3
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8017R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8017R
Lokale Artikelnummer::
BOSSBS-8017R
Beschreibung:
CLN6, a 311 amino acid protein, has seven predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.
VE:
1 * 100 µl
Lieferant:
Cayman Chemical
Beschreibung:
Green CMFDA is a cell-permeable fluorescent probe that freely enters living cells, where it is transformed into a cell-impermeable, soluble, fluorescent compound. The resulting molecule does not affect cell viability or proliferation and stably fluoresces for at least 72 hours, allowing for its use in cell tracking. It is also transferred to daughter cells.
Lieferant:
VWR Collection
Beschreibung:
Die Mikrozentrifugen Micro Star 21 und 21R vereinen Leistung, Vielseitigkeit und Komfort in einem sicheren, kompakten und benutzerfreundlichen Laborgerät. Sowohl die belüftete Micro Star 21 als auch die gekühlte Micro Star 21R sind eine ausgezeichnete Wahl für routinemäßige Probenvorbereitungsprozesse und für High-End-Forschungsanwendungen. Der spezielle Biocontainment-Rotordeckel zum Öffnen und Schließen des Rotors mit einem Klick verkürzt die Probenwechsel im Vergleich zu Schraubdeckeln.
Lieferant:
GREINER BIO ONE
Beschreibung:
PP, ohne Deckel.
Lieferant:
S.C.A.T.
Beschreibung:
Diese Sicherheitststrichter und Container werden weltweit überall dort eingesetzt, wo es um die sichere Entsorgung von flüssigen Abfällen geht. Damit auch die Sammelstellen schnell einsatzbereit sind, wurden die gängigsten Produkte als Sets zusammengestellt. So wird nur eine Teilenummer für das umfassende Sicherheitssystem benötigt, das garantiert kompatibel ist, ohne zeitaufwändige Montage von Einzelteilen.
Lieferant:
GREINER BIO ONE
Beschreibung:
Datamatrix cryo rack for 48 Cryo.s™ storage tubes.
Artikel-Nr:
(BOSSBS-13726R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13726R-A680
Lokale Artikelnummer::
BOSSBS-13726R-A680
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
4-Methoxy-2(5H)-furanon 97%
Artikel-Nr:
(BOSSBS-4183R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4183R-CY3
Lokale Artikelnummer::
BOSSBS-4183R-CY3
Beschreibung:
Rabphilin-3AL (rabphilin-3A-like), also known as RPH3AL or NOC2, is a cytoplasmic Rab GTPase effector. It contains one FYVE-type zinc finger and one Rab-binding (RBD) domain, but unlike its related protein, rabphilin-3A, rabphilin-3AL does not contain any C2 domains. Rabphilin-3AL is expressed in a variety of tissues, with highest levels found in kidney, skeletal muscle, pancreas, liver, ovary, stomach, heart and thyroid. It is believed to play a role regulating calcium-dependent secretory vesicle exocytosis in endocrine and exocrine cells. Via its RBD domain, rabphilin-3AL is capable of binding Rab 27a and, through this interaction, rabphilin-3AL is recruited to dense-core vesicles. With lower affinity, rabphilin-3AL can also bind Rab 3 and Rab 8 with its RBD domain. Through an interaction with Rab 3, rabphilin-3AL can inhibit G-protein signaling in endocrine pancreas and positively regulate insulin secretion. Rabphilin-3AL knockout mice display accumulation of secretory granules and irregular shape in exocrine cells.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
The family of EF-hand type Ca2 -binding proteins includes calbindin, S-100 alpha and beta, calgranulins, B and C, and the parvalbumin family members, including parvalbumin alpha and parvalbumin beta. The S-100 protein is involved in the regulation of cellular processes such as cell cycle progression and differentiation. S-100 protein may function in the activation of Ca2 induced Ca2 release, inhibition of microtubule assembly and inhibition of protein kinase C mediated phosphorylation. Two S-100 subunits, sharing 60% sequence identity, have been described as S-100 alpha chain and S-100 beta chain. Three S-100 dimeric forms have been characterized, differing in their subunit composition of two alpha chains, two beta chains or one alpha and one beta chain. S-100 localizes to the cytoplasm and nuclei of astrocytes, Schwann s cells, ependymomas and astrogliomas. S-100 is also detected in almost all benign naevi, malignant melanocytic tumours and in Langerhans cells in the skin. Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 alpha and beta are present in a variety of other tissues and calbindin is present in intestine and kidney.
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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