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2-Chlor-6-fluor-3-methoxybenzylamin
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2-Chlor-6-fluor-3-methoxybenzylamin
Artikel-Nr:
(BOSSBS-7832R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7832R-CY5
Lokale Artikelnummer::
BOSSBS-7832R-CY5
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9128R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9128R-CY5
Lokale Artikelnummer::
BOSSBS-9128R-CY5
Beschreibung:
CDCA7 is a nuclear protein without a known function, although its high homology with the transcription factor JPO2 or RAM2 suggests that it is also a transcription factor. CDCA7 is one of many target genes regulated by the c-Myc transcription factor. Overexpression of CDCA7 occurs in a significant proportion of cancers and it may play an important role in tumorigenesis. Normally it is periodically expressed in the cell cycle, peaking at the G1 to S phase transition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0572R-PE)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0572R-PE
Lokale Artikelnummer::
BOSSBS-0572R-PE
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7778R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7778R-A555
Lokale Artikelnummer::
BOSSBS-7778R-A555
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7778R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7778R-FITC
Lokale Artikelnummer::
BOSSBS-7778R-FITC
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
<B>Purospher® RP-18</B> ist für die Trennung von problematischen basischen Verbindungen mit einfachen neutralen Eluenten vorgesehen. Außerdem ermöglicht Purospher® RP-18 die Trennung hydrophiler Verbindungen mit wässriger mobiler Phase. Purospher® RP-18 basiert auf einem hochreinen, metallfreien Kieselgel. Die mehrschrittige chemische Modifizierung und Deaktivierung der Oberfläche und das polare Endcapping ermöglichen eine Elution von basischen und chelatbildenden Verbindungen ohne Peaktailing. Purospher® RP-18 ist nicht für die Trennung saurer Verbindungen geeignet. Die gute chemische Stabilität von Purospher® RP-18 ermöglicht über einen langen Zeitraum den Einsatz einer mobilen Phase mit einem pH-Wert von 8.
Artikel-Nr:
(BOSSBS-0572R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0572R-CY5
Lokale Artikelnummer::
BOSSBS-0572R-CY5
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
Tributyrin, is a glycerol substituted with three butyrl esters.
Artikel-Nr:
(41397-100MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
41397-100MG
Lokale Artikelnummer::
SUPL41397-100MG
Beschreibung:
Tebutam CRM kann auch wie folgt verwendet werden:
Optimierung der Probenextraktion basierend auf QuEChERS und dispersiver Festphasenextraktion (d-SPE) zur Reinigung mehrerer Rückstände von 120 Pestiziden, 16 polyzyklischen aromatischen Kohlenwasserstoffen und 22 polychlorierten Biphenylen durch Flüssig- und Gaschromatographie gekoppelt mit Tandem-Massenspektrometrie (MS/MS) Auswertung von 250 Pestizidrückständen, die mit der QuEChERS-Methode aus 103 verarbeiteten Obstproben unter Verwendung von Ultrahochleistungsflüssigkeitschromatographie-Tandem-Massenspektrometrie (UHPLC-MS/MS) extrahiert wurden Bestimmung von 90 Pestiziden, 16 polyzyklischen aromatischen Kohlenwasserstoffen und 22 polychlorierte Biphenyle in Honigproben durch Verwendung von QuEChERS in Kombination mit dispersiver Festphasenextraktion (SPME) zur Probenvorbehandlung und Flüssigchromatographie-Triple-Quadrupol-Tandem-Massenspektrometrie und Gaschromatographie-Ionenfallen-Tandem-Massenspektrometrie zur Quantifizierung Screening und Quantifizierung von 569 Pestiziden in Geißblattproben durch eine Kombination aus Ultrahochleistungsflüssigkeitschromatographie (UHPLC) und Quadrupol-Orbitrap-Hochauflösungs-Massenspektrometrie Gleichzeitige Bestimmung von 134 Pestizidrückständen in Teeproben durch d-SPE-Extraktion mit einem Multifunktionsfilter (MFF), gefolgt von Ultrahochleistungsflüssigchromatographie (UPLC) und Quadrupol-Flugzeit-Massenspektrometrie (TOF-MS).
VE:
1 * 100 mg
Lieferant:
Spectrum Chemical
Beschreibung:
Sodium Citrate, Anhydrous, USP is used to treat certain metabolic problems (acidosis) caused by kidney disease. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Lieferant:
Pall Laboratory
Beschreibung:
Für eine Vielzahl von Anwendungen geeignet, beständig gegen wässrige Lösungen und nicht aggressive organische Lösemittel.
Artikel-Nr:
(BOSSBS-6217R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6217R-CY5.5
Lokale Artikelnummer::
BOSSBS-6217R-CY5.5
Beschreibung:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts. Regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, CRY1 and NR1D1 itself, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, leading to the circadian pattern of clock genes expression. Therefore influences the period length and stability of the clock. Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, including PLIN2 and AVPR1A. Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, such as MMP3. Controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity. In liver, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, steroids and xenobiotics, such as SULT1E1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6217R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6217R-CY7
Lokale Artikelnummer::
BOSSBS-6217R-CY7
Beschreibung:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts. Regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, CRY1 and NR1D1 itself, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, leading to the circadian pattern of clock genes expression. Therefore influences the period length and stability of the clock. Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, including PLIN2 and AVPR1A. Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, such as MMP3. Controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity. In liver, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, steroids and xenobiotics, such as SULT1E1.
VE:
1 * 100 µl
Lieferant:
Sartorius
Beschreibung:
Sartoguard® GF filter elements consist of glass fiber layers and PES membranes. They combine the defined retention performance for particles and microorganisms of membrane filters with the high total throughput capacity in the depth of the fibrous material. They are ideally suited for effective retention of particles, colloids and lipids which block more expensive sterilising grade or Mycoplasma retentive membrane filters quickly.
Artikel-Nr:
(BOSSBS-3091R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3091R
Lokale Artikelnummer::
BOSSBS-3091R
Beschreibung:
The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8325R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8325R-CY5.5
Lokale Artikelnummer::
BOSSBS-8325R-CY5.5
Beschreibung:
Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage, presumably to allow time for DNA repair prior to entry into S and M phase, respectively. The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21. GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, and it apparently acts in concert with GADD 153 in inducing growth arrest. A related DNA-damage inducible gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth. PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage. An additional GADD related gene, PA26, is a possible target of p53. Three isoforms of PA26 have been identified as PA26-T1, PA26-T2 and PA26-T3.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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