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Benzoic+acid-acyl-\\u03B2-D-glucuronide
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Benzoic+acid-acyl-\\u03B2-D-glucuronide
Artikel-Nr:
(ABCAAB80618-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB80618-100
Lokale Artikelnummer::
ABCAAB80618-100
Beschreibung:
N/A
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-0351R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0351R-CY7
Lokale Artikelnummer::
BOSSBS-0351R-CY7
Beschreibung:
Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5018R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5018R-CY3
Lokale Artikelnummer::
BOSSBS-5018R-CY3
Beschreibung:
ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5018R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5018R-CY5
Lokale Artikelnummer::
BOSSBS-5018R-CY5
Beschreibung:
ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI26-042)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-042
Lokale Artikelnummer::
PRSI26-042
Beschreibung:
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. PCDHGC3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1157R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1157R
Lokale Artikelnummer::
BOSSBS-1157R
Beschreibung:
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3321R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3321R-A680
Lokale Artikelnummer::
BOSSBS-3321R-A680
Beschreibung:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukaemia gene, results in chronic myeloproliferative disorder with eosinophilia.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI92-528)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-528
Lokale Artikelnummer::
PRSI92-528
Beschreibung:
The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilises the common gamma chain subunit ( gamma c). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumour infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.
VE:
1 * 50 µG
Artikel-Nr:
(USBIB0003-01D)
Lieferant:
US Biological
Hersteller-Artikelnummer::
B0003-01D
Lokale Artikelnummer::
USBIB0003-01D
Beschreibung:
Anti-BACE2 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1640R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1640R-A647
Lokale Artikelnummer::
BOSSBS-1640R-A647
Beschreibung:
JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.
VE:
1 * 100 µl
Lieferant:
MERCK LIFE SCIENCE
Beschreibung:
ICR/ICRplus contact plates are triple-bagged and gamma irradiated to ensure the highest level of safety when monitoring surfaces in isolators and critical clean rooms for microorganisms.
Artikel-Nr:
(BSENM-1586-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1586-100
Lokale Artikelnummer::
BSENM-1586-100
Beschreibung:
The amyloid beta peptide is derived from the cleavage of the Amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. However, the form(s) of amyloid-beta peptide (Aβ) associated with the pathology characteristic of Alzheimer’s disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an area of considerable research and controversy principally because antibodies thought to be specific for Aβ have been shown to actually detect intraneuronal APP and not Aβ exclusively. MOAB-2 (mouse IgG2b) is a pan-specific, high-titer antibody to Aβ residues 1-4 as demonstrated by biochemical and immunohistochemical analyses (IHC), and is highly specific just to amyloid beta peptide. MOAB-2 did not detect APP or APP-CTFs in cell culture media/lysates (HEK-APPSwe or HEK APPSwe/BACE1) or in brain homogenates from transgenic mice expressing 5 familial AD (FAD) mutation (5xFAD mice). Using IHC on 5xFAD brain tissue, MOAB-2 immunoreactivity co-localized with C-terminal antibodies specific for Aβ40 and Aβ42. MOAB-2 did not co-localize with either N- or C-terminal antibodies to APP. In addition, no MOAB-2-immunreactivity was observed in the brains of 5xFAD/BACE-/- mice, although significant amounts of APP were detected by N- and C-terminal antibodies to APP, as well as by 6E10. In both 5xFAD and 3xTg mouse brain tissue, MOAB-2 co-localized with cathepsin-D, a marker for acidic organelles, further evidence for intraneuronal Aβ, distinct from Aβ associated with the cell membrane. MOAB-2 demonstrated strong intraneuronal and extra-cellular immunoreactivity in 5xFAD and 3xTg mouse brain tissues.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-4135R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4135R-A350
Lokale Artikelnummer::
BOSSBS-4135R-A350
Beschreibung:
TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4135R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4135R-HRP
Lokale Artikelnummer::
BOSSBS-4135R-HRP
Beschreibung:
TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI30-487)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-487
Lokale Artikelnummer::
PRSI30-487
Beschreibung:
Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon¡¡lysine crosslinks. Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. For additional background information on transglutaminases, see TGM1 (MIM 190195).
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-10368R-PE)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10368R-PE
Lokale Artikelnummer::
BOSSBS-10368R-PE
Beschreibung:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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