Naphthol+AS-BI-phosphat+Dinatriumsalz
Artikel-Nr:
(31640-250MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
31640-250MG
Lokale Artikelnummer::
SUPL31640-250MG
Beschreibung:
4,4'-Methylendianilin, Supelco®
VE:
1 * 250 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Bis(4-chlorphenyl)sulfon 99%
Lieferant:
Alfa Aesar
Beschreibung:
1,4-Bis(phenylethynyl)benzene 97%
Lieferant:
Alfa Aesar
Beschreibung:
2-[N,N-Bis(trifluoromethanesulphonyl)amino]-5-chloropyridine 99%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2,2'-Bis(trifluoromethyl)benzidine 97%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methan (BIS-TRIS) ≥99%
Artikel-Nr:
(BOSSBS-5150R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5150R-A350
Lokale Artikelnummer::
BOSSBS-5150R-A350
Beschreibung:
Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Does also incise at AP sites in the DNA strand of DNA/RNA hybrids, single-stranded DNA regions of R-loop structures, and single-stranded RNA molecules. Has a 3'-5' exoribonuclease activity on mismatched deoxyribonucleotides at the 3' termini of nicked or gapped DNA molecules during short-patch BER. Possesses a DNA 3' phosphodiesterase activity capable of removing lesions (such as phosphoglycolate) blocking the 3' side of DNA strand breaks. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Acts as a loading factor for POLB onto non-incised AP sites in DNA and stimulates the 5'-terminal deoxyribose 5'-phosphate (dRp) excision activity of POLB. Plays a role in the protection from granzymes-mediated cellular repair leading to cell death. Also involved in the DNA cleavage step of class switch recombination (CSR). On the other hand, APEX1 also exerts reversible nuclear redox activity to regulate DNA binding affinity and transcriptional activity of transcriptional factors by controlling the redox status of their DNA-binding domain, such as the FOS/JUN AP-1 complex after exposure to IR. Involved in calcium-dependent down-regulation of parathyroid hormone (PTH) expression by binding to negative calcium response elements (nCaREs).
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Bis(3-hydroxyphenyl)disulphide
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3,5-Bis(methylsulphonyl)benzamide 95+%
Artikel-Nr:
(APOSOR939020-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR939020-5G
Lokale Artikelnummer::
APOSOR939020-5G
Beschreibung:
1,2-Bis(phenylsulphinyl)ethane 97%
VE:
1 * 5 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Bis(2,2,3,3,3-pentafluoropropyl)amine 95%
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 4388-22-1
Artikel-Nr:
(BOSSBS-13267R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13267R-A680
Lokale Artikelnummer::
BOSSBS-13267R-A680
Beschreibung:
GALK2 is important in the first step of the galactose metabolism pathway. GALK1, which belongs to the GHMP kinase family of proteins, is a crucial enzyme for galactose metabolism, specifically converting ?d-galactose to galactose 1-phosphate. Defects in the gene encoding GALK1 can cause galactosemia II, an autosomal recessive disorder characterized by congenital cataracts during infancy, often within the first two weeks of life. In the adult population, galactosemia II can cause presenile cataracts that are secondary to accumulation of galactitol in the lens of the eye. A second gene, GALK2, encodes an enzyme with greater activity against GalNAc than galactose. GALK2 has been implicated in the salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13267R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13267R-A750
Lokale Artikelnummer::
BOSSBS-13267R-A750
Beschreibung:
GALK2 is important in the first step of the galactose metabolism pathway. GALK1, which belongs to the GHMP kinase family of proteins, is a crucial enzyme for galactose metabolism, specifically converting ?d-galactose to galactose 1-phosphate. Defects in the gene encoding GALK1 can cause galactosemia II, an autosomal recessive disorder characterized by congenital cataracts during infancy, often within the first two weeks of life. In the adult population, galactosemia II can cause presenile cataracts that are secondary to accumulation of galactitol in the lens of the eye. A second gene, GALK2, encodes an enzyme with greater activity against GalNAc than galactose. GALK2 has been implicated in the salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
3,5-Bis(trifluormethyl)phenylboronsäure ≥97%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3,5-Bis(brommethyl)toluol
Preis auf Anfrage
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