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4-Iodbenzamidin+Hydrochlorid
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4-Iodbenzamidin+Hydrochlorid
Artikel-Nr:
(21095.293)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC21095.293
Beschreibung:
Chrom(III)kaliumsulfat Dodecahydrat ≥97%, GPR RECTAPUR®
VE:
1 * 1 kg
Artikel-Nr:
(PRSI90-360)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-360
Lokale Artikelnummer::
PRSI90-360
Beschreibung:
Kynurenine aminotransferases (KATs) are pyridoxal-5’-phosphate-dependent enzymes that catalyse the conversion of L-kynurenine into kynurenic acid, a neuroactive metabolite whose unbalancing is associated with a number of brain disorders. Biochemical and structural investigations revealed that L-kynurenine (L-KYN) recognition by hKAT II is achieved by exploiting structural features that are peculiar of this isoform, thus offering the possibility to select/design inhibitor molecules specifically targeting hKAT II to be used as modulators of kynurenic acid synthesis in the CNS. hKAT II is one of the aminotransferases involved in the pyridoxal 5'-phosphate (PLP)-dependent irreversible transamination of L-kynurenine (L-KYN) to kynurenic acid (KYNA) in the central nervous system. When assayed in vitro the protein also displays beta-elimination activity.
VE:
1 * 50 µG
Artikel-Nr:
(BLDPBD53080-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD53080-5G
Lokale Artikelnummer::
BLDPBD53080-5G
Beschreibung:
Ethylenedioxybis(trimethylsilane) 98%
VE:
1 * 5 g
Lieferant:
Merck
Beschreibung:
Bromkresolpurpur ACS, Reag. Ph. Eur., Supelco®
Artikel-Nr:
(PRSI29-879)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-879
Lokale Artikelnummer::
PRSI29-879
Beschreibung:
M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-2067R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2067R-CY5.5
Lokale Artikelnummer::
BOSSBS-2067R-CY5.5
Beschreibung:
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, insulin, IGF1, VEGFA and PDGF. Involved in signaling via insulin-receptor substrate (IRS) proteins. Essential in endothelial cell migration during vascular development through VEGFA signaling, possibly by regulating RhoA activity. Required for lymphatic vasculature development, possibly by binding to RAS and by activation by EGF and FGF2, but not by PDGF. Regulates invadopodia formation in breast cancer cells through the PDPK1-AKT1 pathway. Participates in cardiomyogenesis in embryonic stem cells through a AKT1 pathway. Participates in vasculogenesis in embryonic stem cells through PDK1 and protein kinase C pathway. Has also serine-protein kinase activity: phosphorylates PIK3R1 (p85alpha regulatory subunit), EIF4EBP1 and HRAS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2067R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2067R-CY5
Lokale Artikelnummer::
BOSSBS-2067R-CY5
Beschreibung:
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, insulin, IGF1, VEGFA and PDGF. Involved in signaling via insulin-receptor substrate (IRS) proteins. Essential in endothelial cell migration during vascular development through VEGFA signaling, possibly by regulating RhoA activity. Required for lymphatic vasculature development, possibly by binding to RAS and by activation by EGF and FGF2, but not by PDGF. Regulates invadopodia formation in breast cancer cells through the PDPK1-AKT1 pathway. Participates in cardiomyogenesis in embryonic stem cells through a AKT1 pathway. Participates in vasculogenesis in embryonic stem cells through PDK1 and protein kinase C pathway. Has also serine-protein kinase activity: phosphorylates PIK3R1 (p85alpha regulatory subunit), EIF4EBP1 and HRAS.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD115311-100MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD115311-100MG
Lokale Artikelnummer::
BLDPBD115311-100MG
Beschreibung:
Bendamustine hydrochloride 99%
VE:
1 * 100 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Methoxy(cyclooctadiene)iridium(I) dimer 97%
Lieferant:
BLD PHARMATECH GMBH
Beschreibung:
Azure II BS
Lieferant:
Alfa Aesar
Beschreibung:
Hexamethyldisilathian, tech.
Artikel-Nr:
(05200.185)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC05200.185
Beschreibung:
28 Elemente 1 mg/L: Al, Ag, As, B, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Mo, Na, Ni, Pb, Sb, Se, Sr, Ti, Tl, V, Zn.
VE:
1 * 100 mL
Artikel-Nr:
(BOSSBS-5453R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5453R-CY3
Lokale Artikelnummer::
BOSSBS-5453R-CY3
Beschreibung:
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
3,3'-Dimethylbenzidin Dihydrochorid 99%
Lieferant:
Thermo Scientific
Beschreibung:
EGTA-Na4 (Ethylenglycolbis(2-aminoethylether)-N,N,N',N'-tetraessigsäureTetranatriumsalz) 95%
Artikel-Nr:
(BLDPBD156910-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD156910-1G
Lokale Artikelnummer::
BLDPBD156910-1G
Beschreibung:
Z-Dap(Z)-OH 97%
VE:
1 * 1 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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