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PAW+BIOSCIENCE
Artikel-Nr:
(QEDB30103)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
30103
Lokale Artikelnummer::
QEDB30103
Beschreibung:
Anti-FGFR1 Mouse Monoclonal Antibody
VE:
1 * 250 µG
Artikel-Nr:
(QEDB11573)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
11573
Lokale Artikelnummer::
QEDB11573
Beschreibung:
Anti-ASIC1 Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(QEDB11079)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
11079
Lokale Artikelnummer::
QEDB11079
Beschreibung:
Anti-CRYAB Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(QEDB56527)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
56527
Lokale Artikelnummer::
QEDB56527
Beschreibung:
Anti-ADAM22 Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(QEDB11119)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
11119
Lokale Artikelnummer::
QEDB11119
Beschreibung:
Anti-HSPA8 Mouse Monoclonal Antibody
VE:
1 * 100 µG
Lieferant:
Tonbo Biosciences
Beschreibung:
The O323 antibody reacts with human CD27 (TNFRSF7), a cell surface homodimer of 55 kDa subunits, which provides co-stimulatory signaling in support of the T cell (TCR) and B cell (BCR) receptors. By comparison with CD28, whose TCR co-stimulatory signal can trigger cell proliferation, CD27 signaling appears to promote cell survival and differentiation to effector / memory stages. Also in contrast with CD28, the CD27 receptor may be shed following interaction with its ligand CD70, which is typically expressed on activated dendritic cells, T cells and B cells. With respect to B cells, CD27 is considered to be a phenotypic marker for memory B cells. CD27 has been included within a group of phenotypic markers for identifying human B regulatory cells (Bregs), a cell type proposed to regulate CD4+ T cell proliferation and Foxp3 / CTLA-4 expression in Treg cells.
Lieferant:
Tonbo Biosciences
Beschreibung:
The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Lieferant:
Tonbo Biosciences
Beschreibung:
The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Lieferant:
Tonbo Biosciences
Beschreibung:
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
Lieferant:
Tonbo Biosciences
Beschreibung:
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
Lieferant:
Tonbo Biosciences
Beschreibung:
The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.
Lieferant:
Tonbo Biosciences
Beschreibung:
The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Artikel-Nr:
(QEDB11572)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
11572
Lokale Artikelnummer::
QEDB11572
Beschreibung:
Anti-TARPgamma2/4/8/Stargazin Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(QEDB56547)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
56547
Lokale Artikelnummer::
QEDB56547
Beschreibung:
Anti-GluA1-GluR1 Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(QEDB11531)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
11531
Lokale Artikelnummer::
QEDB11531
Beschreibung:
Anti-Kir2.1 K+ Channel Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(QEDB56468)
Lieferant:
QED Bioscience
Hersteller-Artikelnummer::
56468
Lokale Artikelnummer::
QEDB56468
Beschreibung:
Anti-pan-Shank Mouse Monoclonal Antibody
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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