PAW+BIOSCIENCE
Artikel-Nr:
(786-453)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-453
Lokale Artikelnummer::
GENO786-453
Beschreibung:
The Phosphatase Assay Kit is designed to measure the activity of phosphatases in biological samples and to screen for agonists and inhibitors of phosphatases. The Phosphatase Assay Kit uses para-nitrophenyl phosphate (pNPP), a chromogenic substrate for most phosphatases, including alkaline phosphatases, acid phosphatases, protein tyrosine phosphatases and serine/threonine phosphatases.
VE:
1 * 1 KIT
Artikel-Nr:
(BE-104)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
BE-104
Lokale Artikelnummer::
GENOBE-104
Beschreibung:
This DNA fingerprinting kit allows students to carry out their own criminal investigation by comparing DNA samples collected from suspects to DNA collected at a pseudo-crime scene.
VE:
1 * 1 KIT
Artikel-Nr:
(786-213)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-213
Lokale Artikelnummer::
GENO786-213
Beschreibung:
CytoScan™-SRB Cytotoxicity Assay is based upon the quantitative staining of cellular proteins by sulforhodamine B (SRB). The assay is used for cell density determination, based on the measurement of cellular protein content.
VE:
1 * 1.000 Assays
Lieferant:
G-Biosciences
Beschreibung:
Protein A or G binding/wash buffer
Lieferant:
Tonbo Biosciences
Beschreibung:
The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The GK1.5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the GK1.5 antibody and an alternative antibody, Anti-Mouse CD4 clone RM4-5, will "compete" for binding, i.e. RM4-5 is able to block GK1.5 binding to cells. In contrast, the Anti-Mouse CD4 clone RM4-4 does not block binding of the GK1.5 antibody to cells (Arora S et al. 2006. Infect. Immun. 74: 4339-4348). The GK1.5 antibody is also reported to be cross-reactive with Syrian hamster CD4.
Lieferant:
Tonbo Biosciences
Beschreibung:
The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.
Artikel-Nr:
(786-677)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-677
Lokale Artikelnummer::
GENO786-677
Beschreibung:
Swift™ Membrane Stain is a unique, proprietary (patents pending), rapid, reversible, ready-to-use membrane stain for proteins on nitrocellulose or PVDF membranes. Swift™ Membrane Stain stains proteins faster and with 500 times more sensitivity than the routinely used Ponceau-S stain and other commercially available protein stains.
VE:
1 * 1 KIT
Lieferant:
Tonbo Biosciences
Beschreibung:
The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.
Lieferant:
Tonbo Biosciences
Beschreibung:
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte "rolling" on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research. The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
Lieferant:
G-Biosciences
Beschreibung:
This Sulphhydryl Immobilisation Kit is designed for the coupling of sulphhydryl containing peptides to a solid agarose support. The sulphhydryl coupling resin columns utilises iodoacetyl groups that specifically react with free sulphhydryls to form covalent, permanent thioether bonds.
Lieferant:
G-Biosciences
Beschreibung:
Diese vorgemischten, gebrauchsfertigen Gel-Ladepuffer wurden entwickelt, um den Gebrauch von Ethidiumbromid zu minimieren. Glow-Farbstoffe liefern intensive DNA/RNA-Banden mit geringem Hintergrund und minimaler Bandenverzerrung auf jeder Art von Agarose- oder Acrylamid-Gel.
Lieferant:
G-Biosciences
Beschreibung:
TEMED (N,N,N’,N’-Tetramethylethylenediamine) is a 99,9% pure polymerisation reagent used when making polyacrylamide gels used in gel electrophoresis.
Artikel-Nr:
(OZBIMT01000)
Lieferant:
OZ BIOSCIENCES
Hersteller-Artikelnummer::
MT01000
Lokale Artikelnummer::
OZBIMT01000
Beschreibung:
MTT cell proliferation assay kit is designed for spectrophotometric quantification of cell growth, viability and proliferation and can be used as a direct indicator of cytotoxicity (such as for screening anticancer drugs) and apoptosis.
VE:
1 * 1 KIT
Lieferant:
JENA BIOSCIENCES
Beschreibung:
Uridin-5'-triphosphorsäure Trinatriumsalz (UTP-Na<sub>3</sub>)
Lieferant:
Tonbo Biosciences
Beschreibung:
The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The GK1.5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the GK1.5 antibody and an alternative antibody, Anti-Mouse CD4 clone RM4-5, will "compete" for binding, i.e. RM4-5 is able to block GK1.5 binding to cells. In contrast, the Anti-Mouse CD4 clone RM4-4 does not block binding of the GK1.5 antibody to cells (Arora S et al. 2006. Infect. Immun. 74: 4339-4348). The GK1.5 antibody is also reported to be cross-reactive with Syrian hamster CD4.
Lieferant:
Tonbo Biosciences
Beschreibung:
The C17.8 antibody is specific for the 40 kDa (p40) protein subunit shared by the cytokines IL-12 and IL-23. To form IL-12, p40 assembles with a separate 35 kDa protein known as p35, resulting in a 70 kDa functional cytokine. IL-12 is secreted by activated monocytes, macrophages, and dendritic cells, and has been shown to target naïve, resting CD4+ T cells to promote their proliferation and secretion of cytokines. IL-23 contains the p40 subunit in combination with a 19 kDa protein chain, p19; its primary source being activated dendritic cells and other antigen-presenting cells. IL-23 appears to target different cell types than IL-12, acting on memory CD4+ T cells to induce a strong proliferative response and contributing to the generation and expansion of Th17 cells. Like the cytokines themselves, the receptors for IL-12 and IL-23 share one subunit, as well as containing distinct cytokine-specific subunits.
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