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1,4-Dithian-2,5-diol
Artikel-Nr:
(BOSSBS-13191R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13191R-A680
Lokale Artikelnummer::
BOSSBS-13191R-A680
Beschreibung:
FNDC3A is a 1,134 amino acid protein that belongs to the FNDC3 family of proteins. FNDC3A contains an N-terminal proline-rich region, nine fibronectin type-III domains (none of which contain an RGD sequence) and a hydrophobic C-terminal transmembranous helix. Expressed in a wide variety of tissues, FNDC3A localizes to Golgi vesicles and to the developing acrosome of spermatids. FNDC3A is believed to function in glycosaminoglycan and collagen synthesis. In mice, a mutation in the gene encoding FNDC3A causes male sterility due to defective adhesion between Sertoli cells and spermatids in the seminiferous epithelium. This suggests that FNDC3A plays an important role in spermatogenesis, possibly mediating or maintaining the adhesion between Sertoli cells and spermatids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12161R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12161R-CY5
Lokale Artikelnummer::
BOSSBS-12161R-CY5
Beschreibung:
CAPS1 is a 189 amino acid cytoplasmic protein that contains four EF-hand domains, which serve as calcium-binding sites, and was first identified in canine thyroid. Interestingly, CAPS1 is much less abundant in humans than in canines. Synthesis and phosphorylation of CAPS1 is upregulated by cAMP-agonists in thyrocytes. CAPS1 likely functions in the regulation of ionic transport and may be involved in cross-signaling between cAMP and Ca(+2)-phophatidylinositol cascades. In addition to thyriod, CAPS1 is expressed in brain, salivary glands and lung. Expression of CAPS1 is increased in endometrial cancer and prognosis seems to be dependent on the level of CAPS1 expression, indicating that CAPS1 may be an appropriate prognostic marker for patient survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9585R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9585R-CY3
Lokale Artikelnummer::
BOSSBS-9585R-CY3
Beschreibung:
Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11316R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11316R-A555
Lokale Artikelnummer::
BOSSBS-11316R-A555
Beschreibung:
Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. SAPAP3 (PSD-95/SAP90-binding protein 3), also known as DLGAP3 (disks large-associated protein 3) or DAP3, is a 979 amino acid protein that belongs to the SAPAP family of PSD-95/SAP90-associated proteins. Localized to the cell junction, as well as to the peripheral membrane and the cell synapse, SAPAP3 is thought to play a role in the organization of neuronal cell signaling and synapses, and may also function as an adaptor protein, possibly linking ion channels with the cytoskeleton.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13602R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13602R-CY7
Lokale Artikelnummer::
BOSSBS-13602R-CY7
Beschreibung:
SLAIN1 is a 561 amino acid member of the SLAIN motif-containing family and is expressed in embryonic stem cells, as well as in lung, brain and testis, where it exists as two alternatively spliced isoforms. The gene encoding SLAIN1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13165R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13165R-HRP
Lokale Artikelnummer::
BOSSBS-13165R-HRP
Beschreibung:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11414R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11414R-A680
Lokale Artikelnummer::
BOSSBS-11414R-A680
Beschreibung:
ZNF318 is a 2279 amino acid endocrine regulatory protein that localizes to the nucleus. Highly expressed in testis, ovaries and kidneys, ZNF318 is a co-repressor of androgen receptor (AR)-mediated transcriptional activation and is thought to regulate transcription during spermatogenesis. ZNF318 interacts with the N-terminal domain of AR and contains two matrin-type zinc fingers. Two isoforms of ZNF318, designated TZF and TZF-L, are produced due to alternative splicing events. Each of these splice variants are thought to have unique roles in transcriptional regulation. While the TZF isoform functions as a repressor of AR-mediated transcriptional activation, the TZF-L isoform is thought to enhance AR-mediated transcriptional activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13608R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13608R-FITC
Lokale Artikelnummer::
BOSSBS-13608R-FITC
Beschreibung:
CEP57 (centrosomal protein 57kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88% sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13191R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13191R-A647
Lokale Artikelnummer::
BOSSBS-13191R-A647
Beschreibung:
FNDC3A is a 1,134 amino acid protein that belongs to the FNDC3 family of proteins. FNDC3A contains an N-terminal proline-rich region, nine fibronectin type-III domains (none of which contain an RGD sequence) and a hydrophobic C-terminal transmembranous helix. Expressed in a wide variety of tissues, FNDC3A localizes to Golgi vesicles and to the developing acrosome of spermatids. FNDC3A is believed to function in glycosaminoglycan and collagen synthesis. In mice, a mutation in the gene encoding FNDC3A causes male sterility due to defective adhesion between Sertoli cells and spermatids in the seminiferous epithelium. This suggests that FNDC3A plays an important role in spermatogenesis, possibly mediating or maintaining the adhesion between Sertoli cells and spermatids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11670R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11670R-FITC
Lokale Artikelnummer::
BOSSBS-11670R-FITC
Beschreibung:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12161R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12161R-A680
Lokale Artikelnummer::
BOSSBS-12161R-A680
Beschreibung:
CAPS1 is a 189 amino acid cytoplasmic protein that contains four EF-hand domains, which serve as calcium-binding sites, and was first identified in canine thyroid. Interestingly, CAPS1 is much less abundant in humans than in canines. Synthesis and phosphorylation of CAPS1 is upregulated by cAMP-agonists in thyrocytes. CAPS1 likely functions in the regulation of ionic transport and may be involved in cross-Signalling between cAMP and Ca²⁺-phophatidylinositol cascades. In addition to thyriod, CAPS1 is expressed in brain, salivary glands and lung. Expression of CAPS1 is increased in endometrial cancer and prognosis seems to be dependent on the level of CAPS1 expression, indicating that CAPS1 may be an appropriate prognostic marker for patient survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13166R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13166R-A350
Lokale Artikelnummer::
BOSSBS-13166R-A350
Beschreibung:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1503R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1503R-A488
Lokale Artikelnummer::
BOSSBS-1503R-A488
Beschreibung:
This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterised by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [FUNCTION] Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13595R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13595R-A680
Lokale Artikelnummer::
BOSSBS-13595R-A680
Beschreibung:
DPPA4 (developmental pluripotency associated 4) is a 304 amino acid protein that localizes to the nucleus and is thought to be involved in the maintenance of cell pluripotentiality during embryogenesis. The gene encoding DPPA4 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9100R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9100R-CY5
Lokale Artikelnummer::
BOSSBS-9100R-CY5
Beschreibung:
Arylsulfatase F, also known as ARSF, is a 590 amino acid secretory protein that belongs to the sulfatase family of bone and cartilage matrix proteins. Arylsulfatase F uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The activity of Arylsulfatase F, unlike that of other family members, such as Arylsulfatase E, is not inhibited by warfarin. The gene encoding Arylsulfatase F maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8857R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8857R-A488
Lokale Artikelnummer::
BOSSBS-8857R-A488
Beschreibung:
NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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