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Potassium+2-(trifluoromethyl)phenyltrifluoroborate
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Potassium+2-(trifluoromethyl)phenyltrifluoroborate
Artikel-Nr:
(BOSSBS-7689R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7689R-A680
Lokale Artikelnummer::
BOSSBS-7689R-A680
Beschreibung:
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca2+/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13029R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13029R
Lokale Artikelnummer::
BOSSBS-13029R
Beschreibung:
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP3 (dipeptidyl-peptidase 3), also known as DPPIII, is a zinc-exopeptidase that belongs to the peptidase M49 family. DPP3 localizes to the cytoplasm and is involved in intracellular protein catabolism. More specifically, DPP3 is an important enzyme involved in the degradation of enkephalins. An increase in the activity of DPP3 is implicated in ovarian and endometrial cancers.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
3-(Trifluormethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazin ≥98%
Artikel-Nr:
(APOSPC440009-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC440009-100MG
Lokale Artikelnummer::
APOSPC440009-100MG
Beschreibung:
(S)-3,3'-Bis[3,5-bis(trifluoromethyl)phenyl]-1,1'-binaphthyl-2,2'-diyl-N-triflyl phosphoramide
VE:
1 * 100 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Methyl-4-(trifluormethyl)-1,3-thiazol-5-carbonsäure
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Methoxy-3-(trifluormethyl)benzoesäure
Lieferant:
Thermo Orion
Beschreibung:
These potassium electrodes are designed to measure potassium in aqueous solutions simply, accurately and economically.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
6,7-Dichlor-2-methyl-3-(trifluormethyl)chinoxalin 97%
Artikel-Nr:
(APOSPC6078-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC6078-25G
Lokale Artikelnummer::
APOSPC6078-25G
Beschreibung:
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluormethyl)anilin 98%
VE:
1 * 25 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4,8-Dichlor-6-(trifluormethyl)chinolin 95+%
Artikel-Nr:
(PERC04810949)
Lieferant:
PERKIN ELMER GC INSTRUMENTS
Hersteller-Artikelnummer::
04810949
Lokale Artikelnummer::
PERC04810949
Beschreibung:
Potassium bromide pellet holder
VE:
1 * 1 ST
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Brom-4-(trifluormethyl)benzoesäure 97%
Artikel-Nr:
(BOSSBS-11733R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-A555
Lokale Artikelnummer::
BOSSBS-11733R-A555
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11733R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-A350
Lokale Artikelnummer::
BOSSBS-11733R-A350
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11733R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-A647
Lokale Artikelnummer::
BOSSBS-11733R-A647
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12070R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12070R-CY7
Lokale Artikelnummer::
BOSSBS-12070R-CY7
Beschreibung:
Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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