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3-Bromothiophene-4-sulphonyl+chloride
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3-Bromothiophene-4-sulphonyl+chloride
Artikel-Nr:
(BOSSBS-0549R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0549R-A750
Lokale Artikelnummer::
BOSSBS-0549R-A750
Beschreibung:
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3349R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3349R-A647
Lokale Artikelnummer::
BOSSBS-3349R-A647
Beschreibung:
postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0441R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0441R-A750
Lokale Artikelnummer::
BOSSBS-0441R-A750
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0441R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0441R-A488
Lokale Artikelnummer::
BOSSBS-0441R-A488
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0236R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0236R-A647
Lokale Artikelnummer::
BOSSBS-0236R-A647
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(SCTV310032)
Lieferant:
S.C.A.T.
Hersteller-Artikelnummer::
310032
Lokale Artikelnummer::
SCTV310032
Beschreibung:
Spezielle Version der SafetyCaps V2.0 für den Einsatz in der präparativen HPLC-Umgebung mit größeren Schlauchanschlüssen und Belüftungsventilen mit höherer Flussrate.
VE:
1 * 1 ST
Lieferant:
Alfa Aesar
Beschreibung:
Aluminiumchlorid, wasserfrei ≥99,985% (Metall-Basis)
Artikel-Nr:
(BOSSBS-0651R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0651R-CY5.5
Lokale Artikelnummer::
BOSSBS-0651R-CY5.5
Beschreibung:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6767R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6767R-A555
Lokale Artikelnummer::
BOSSBS-6767R-A555
Beschreibung:
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(USBIA2298-20J)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A2298-20J
Lokale Artikelnummer::
USBIA2298-20J
Beschreibung:
Anti-SERPINC1 Mouse Monoclonal Antibody [clone: 6F217]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1803R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1803R-CY3
Lokale Artikelnummer::
BOSSBS-1803R-CY3
Beschreibung:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(87832.180)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC87832.180
Beschreibung:
Ammoniumeisen(III)sulfat-Lösung R6 R6 Reag. Ph. Eur. 1037705
VE:
1 * 100 mL
Artikel-Nr:
(80104.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
80104
Lokale Artikelnummer::
BTIU80104
Beschreibung:
The principle of DPA/Tb3 for vesicle fusion assay is based on the fact that contact of the chelator dipicolinic acid (DPA) with terbium (III) forms an instant Tb3 -DPA complex that is ~10,000 times more fluorescent than free Tb3 . In the assay, separate vesicle populations are loaded with 2.5 mM TbCl3 in 50 mM sodium citrate, or 50 mM DPA in 20 mM NaCl.
VE:
1 * 1 SET
Artikel-Nr:
(BOSSBS-6763R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6763R-A647
Lokale Artikelnummer::
BOSSBS-6763R-A647
Beschreibung:
Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
VE:
1 * 100 µl
Lieferant:
Tonbo Biosciences
Beschreibung:
The 2.4G2 antibody is specific for a common epitope found in the extracellular regions of mouse Fc-receptors Fc-gamma II (CD32) and Fc-gamma III (CD16). These receptors are expressed by B cells, monocytes, macrophages, NK cells, dendritic cells, and neutrophils.
Artikel-Nr:
(BOSSBS-11104R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11104R
Lokale Artikelnummer::
BOSSBS-11104R
Beschreibung:
Neurexins comprise a family of neuronal cell surface proteins, which include neurexin I (NRXN1), neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV). Neurexins I-III are expressed as a and b isoforms. The a isoforms are made of three cassettes, which contain two LNS (Laminin A, Neurexins, Sex hormone-binding)-domains separated by EGF domains, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal. The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin. The b isoforms have only one LNS-domain, bind to neuroligins, and play a role in the formation and remodeling of synapes. Caspr (for Contactin-Associated Protein 1, also designated Paranodin in mouse), contains an extracellular domain similar to the other three neurexins, and binds to the surface glycoprotein Contactin. Caspr and the closely related Caspr2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. Specifically, Caspr exists at the paranodal junctions, while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region. Caspr may play a role in the communication of glial cells and neurons during development.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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