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Pyrazolo[1,5-a]pyrimidin-7(4H)-one
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Pyrazolo[1,5-a]pyrimidin-7(4H)-one
Artikel-Nr:
(BOSSBS-13339R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13339R-CY5
Lokale Artikelnummer::
BOSSBS-13339R-CY5
Beschreibung:
GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0522R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0522R-A555
Lokale Artikelnummer::
BOSSBS-0522R-A555
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3'-Bromo-2'-methoxy-2,2,2-trifluoroacetophenone 97%
Lieferant:
BLD PHARMATECH GMBH
Beschreibung:
(4-Methoxyphenyl)aceton 98%
Artikel-Nr:
(PPSA3500947)
Lieferant:
PFENNIG REINIGUNGSTECHNIK
Hersteller-Artikelnummer::
3500947
Lokale Artikelnummer::
PPSA3500947
Beschreibung:
One way disposable mop for cleanroom sword CR/A.
VE:
1 * 5 ST
New Product
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Fluoro-2-butanone 97%
Artikel-Nr:
(BOSSBS-11841R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11841R-CY7
Lokale Artikelnummer::
BOSSBS-11841R-CY7
Beschreibung:
TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR27582-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR27582-100G
Lokale Artikelnummer::
APOSOR27582-100G
Beschreibung:
2,6-Dimethyl-4-pyron
VE:
1 * 100 g
Lieferant:
Alfa Aesar
Beschreibung:
5-Methoxy-1-indanon ≥98%
Artikel-Nr:
(BLDPBD56264-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD56264-5G
Lokale Artikelnummer::
BLDPBD56264-5G
Beschreibung:
1-(Adamantan-1-yl)ethanon 98%
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-12330R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12330R-A350
Lokale Artikelnummer::
BOSSBS-12330R-A350
Beschreibung:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å and IFN-∫, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9380R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9380R-CY5
Lokale Artikelnummer::
BOSSBS-9380R-CY5
Beschreibung:
Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects. OS-I mutations produce proteins with a decreased affinity for microtubules.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
4'-Iodacetophenon 98%
Lieferant:
Thermo Scientific
Beschreibung:
2,4-Diamino-6-hydroxypyrimidine 96%
Artikel-Nr:
(BOSSBS-0522R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0522R-A750
Lokale Artikelnummer::
BOSSBS-0522R-A750
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13339R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13339R-A488
Lokale Artikelnummer::
BOSSBS-13339R-A488
Beschreibung:
GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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