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Pyridin-N-oxid
Artikel-Nr:
(BOSSBS-2537R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2537R-CY5.5
Lokale Artikelnummer::
BOSSBS-2537R-CY5.5
Beschreibung:
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2537R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2537R-A488
Lokale Artikelnummer::
BOSSBS-2537R-A488
Beschreibung:
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4192R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4192R-A350
Lokale Artikelnummer::
BOSSBS-4192R-A350
Beschreibung:
SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4192R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4192R
Lokale Artikelnummer::
BOSSBS-4192R
Beschreibung:
SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
VE:
1 * 100 µl
Lieferant:
VWR Chemicals
Beschreibung:
Natriummolybdat(VI) Dihydrat ≥99,0%, GPR RECTAPUR®
Artikel-Nr:
(0541-250G)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC0541-250G
Beschreibung:
Natriummolybdat(VI) Dihydrat ≥99,5% ACS
VE:
1 * 250 g
Artikel-Nr:
(BOSSBS-11297R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11297R-A750
Lokale Artikelnummer::
BOSSBS-11297R-A750
Beschreibung:
catalyses the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR340032-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR340032-250MG
Lokale Artikelnummer::
APOSOR340032-250MG
Beschreibung:
(R)-3,3'-Bis(anthracenyl-9-yl)-1,1'-binapthyl-2,2'-diyl hydrogenphosphate
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-6716R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6716R-A488
Lokale Artikelnummer::
BOSSBS-6716R-A488
Beschreibung:
Uricase catalyzes the oxidation of uric acid to 5 hydroxyisourate which spontaneously decomposes to form allantoin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12461R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12461R-CY5
Lokale Artikelnummer::
BOSSBS-12461R-CY5
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13387R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13387R-CY5
Lokale Artikelnummer::
BOSSBS-13387R-CY5
Beschreibung:
Glucose Oxidase is a dimeric enzyme that binds to β-D-glucose and aids in its oxidation into D-glucono-1,5-lactone which then hydrolyzes to gluconic acid. Flavin adenine dinucleotide (FAD) is a cofactor to Glucose Oxidase that acts as the initial electron acceptor and is required for this oxidation to occur. Glucose Oxidase is a natural preservative found in honey, where it reduces atmospheric oxygen into hydrogen peroxide which acts as an antibacterial barrier. Glucose Oxidase is also commonly used in biosensors in which it conveys levels of glucose by keeping track of the number of electrons passed through the enzyme. In this application, Glucose Oxidase is connected to an electrode and the resulting charge is measured.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4192R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4192R-A488
Lokale Artikelnummer::
BOSSBS-4192R-A488
Beschreibung:
SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Diphenylphosphonat (contains varying amounts of phenol and (C₆H₅O)₃P)
Lieferant:
Alfa Aesar
Beschreibung:
Potassium bis(oxalato)oxotitanate(IV) dihydrate
Lieferant:
Thermo Scientific
Beschreibung:
Kaliumwolframat 99.95% -100 mesh für die Spurenanalytik von Metallen
Artikel-Nr:
(BOSSBS-8552R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8552R-HRP
Lokale Artikelnummer::
BOSSBS-8552R-HRP
Beschreibung:
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).Involvement in disease;Defects in XDH are the cause of xanthinuria type 1 (XU1) . Xanthinuria is characterized by excretion of very large amounts of xanthine in the urine and a tendency to form xanthine stones. Uric acid is strikingly diminished in serum and urine. XU1 is due to isolated xanthine dehydrogenase. XU1 patients can metabolize allopurinol.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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