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Quecksilber(II)trifluormethansulfonat
Artikel-Nr:
(BOSSBS-9055R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9055R-A647
Lokale Artikelnummer::
BOSSBS-9055R-A647
Beschreibung:
DR1, also known as NC2∫ (negative cofactor 2 subunit ∫), is a TFIID (TATA box-binding protein)-associated protein. DR1 localizes to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated in vivo.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3097R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3097R-A555
Lokale Artikelnummer::
BOSSBS-3097R-A555
Beschreibung:
Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g. TNF-inducible RELA/p65 activation and IL-6-inducible STAT3 signaling). Promotes RNA synthesis in genetic programs for cell growth, differentiation and viral pathogenesis. P-TEFb is also involved in cotranscriptional histone modification, mRNA processing and mRNA export. Modulates a complex network of chromatin modifications including histone H2B monoubiquitination (H2Bub1), H3 lysine 4 trimethylation (H3K4me3) and H3K36me3; integrates phosphorylation during transcription with chromatin modifications to control co-transcriptional histone mRNA processing. The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro. Replication stress response protein; the CDK9/cyclin-K complex is required for genome integrity maintenance, by promoting cell cycle recovery from replication arrest and limiting single-stranded DNA amount in response to replication stress, thus reducing the breakdown of stalled replication forks and avoiding DNA damage. In addition, probable function in DNA repair of isoform 2 via interaction with KU70/XRCC6. Promotes cardiac myocyte enlargement.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3097R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3097R-A680
Lokale Artikelnummer::
BOSSBS-3097R-A680
Beschreibung:
Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g. TNF-inducible RELA/p65 activation and IL-6-inducible STAT3 signaling). Promotes RNA synthesis in genetic programs for cell growth, differentiation and viral pathogenesis. P-TEFb is also involved in cotranscriptional histone modification, mRNA processing and mRNA export. Modulates a complex network of chromatin modifications including histone H2B monoubiquitination (H2Bub1), H3 lysine 4 trimethylation (H3K4me3) and H3K36me3; integrates phosphorylation during transcription with chromatin modifications to control co-transcriptional histone mRNA processing. The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro. Replication stress response protein; the CDK9/cyclin-K complex is required for genome integrity maintenance, by promoting cell cycle recovery from replication arrest and limiting single-stranded DNA amount in response to replication stress, thus reducing the breakdown of stalled replication forks and avoiding DNA damage. In addition, probable function in DNA repair of isoform 2 via interaction with KU70/XRCC6. Promotes cardiac myocyte enlargement.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-108-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-108-100
Lokale Artikelnummer::
BSENR-108-100
Beschreibung:
DBH is an oxireductase belonging to the copper type II ascorbate-dependent monooxygenase family. DBH exists as a homotetramer composed of two non-covalently bound disulfide-linked dimers. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It binds 2 copper ions and 1 PQQ per subunit . Depending on the presence of a signal peptide, DBH can exist in both soluble and membrane-bound forms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2214R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2214R-HRP
Lokale Artikelnummer::
BOSSBS-2214R-HRP
Beschreibung:
This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(USBIC2085-63K-BIOT)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C2085-63K-BIOT
Lokale Artikelnummer::
USBIC2085-63K-BIOT
Beschreibung:
Anti-CSNK2A1 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-7780R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7780R-FITC
Lokale Artikelnummer::
BOSSBS-7780R-FITC
Beschreibung:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7780R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7780R-A647
Lokale Artikelnummer::
BOSSBS-7780R-A647
Beschreibung:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6076R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6076R-CY3
Lokale Artikelnummer::
BOSSBS-6076R-CY3
Beschreibung:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7978R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7978R-A750
Lokale Artikelnummer::
BOSSBS-7978R-A750
Beschreibung:
This gene is a member of the brain expressed X-linked gene family. The proteins encoded by some of the other members of this family act as transcription elongation factors which allow RNA polymerase II to escape pausing during elongation. Multiple alternatively spliced variants, encoding the same protein, have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6295R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6295R-CY5.5
Lokale Artikelnummer::
BOSSBS-6295R-CY5.5
Beschreibung:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7070R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7070R-CY7
Lokale Artikelnummer::
BOSSBS-7070R-CY7
Beschreibung:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7070R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7070R-CY5
Lokale Artikelnummer::
BOSSBS-7070R-CY5
Beschreibung:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13490R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13490R-CY7
Lokale Artikelnummer::
BOSSBS-13490R-CY7
Beschreibung:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi-resident protein. It may process proteins synthesized in the rough endoplasmic reticulum and assist in the transport of protein cargo through the Golgi apparatus. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1603R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1603R-CY5.5
Lokale Artikelnummer::
BOSSBS-1603R-CY5.5
Beschreibung:
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
VE:
1 * 100 µl
Lieferant:
GOLD STANDARD DIAGNOSTICS
Beschreibung:
This RT-PCR assay is a highly sensitive Multiplex Real-Time PCR with CE-IVD marking for the direct qualitative pathogen detection of SARS-CoV-2 genomic RNA in respiratory samples.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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