Sodium-4-aminoazobenzene-4\'-sulphonate
Artikel-Nr:
(PERCN9300152)
Lieferant:
PERKIN ELMER GC INSTRUMENTS
Hersteller-Artikelnummer::
N9300152
Lokale Artikelnummer::
PERCN9300152
Beschreibung:
Sodium Standard, 1000 mg/L, Natrium, Matrix: 2% HNO₃, Anwendung: ICP-Standards, AAS-Standards
VE:
1 * 1 ST
Lieferant:
Merck
Beschreibung:
Sodium-(S)-lactate-solution about 50%
Artikel-Nr:
(BOSSBS-12313R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12313R-HRP
Lokale Artikelnummer::
BOSSBS-12313R-HRP
Beschreibung:
The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15968R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15968R-FITC
Lokale Artikelnummer::
BOSSBS-15968R-FITC
Beschreibung:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localised at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organisation. Adducin Alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Alpha and Adducin Gamma is ubiquitous in contrast to the restricted expression of Adducin Beta. Adducin Beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.
VE:
1 * 100 µl
Artikel-Nr:
(J61934.AK)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J61934.AK
Lokale Artikelnummer::
ALFAJ61934.AK
Beschreibung:
Sodium acetate, 3M aq, solution, pH 7,0, RNAse free, Liquid
VE:
1 * 250 mL
Artikel-Nr:
(BOSSBS-11954R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11954R
Lokale Artikelnummer::
BOSSBS-11954R
Beschreibung:
Myo-inositol is involved in many important aspects of cellular regulation including membrane structure, signal transduction and osmoregulation. It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT). SMIT activity maintains intracellular concentrations of myo-inositol; it is upregulated in response to hypertonic stress. The human SMIT protein is encoded by the SLC5A3 gene, which maps to chromosome 21q22.12. It is expressed in many human tissues, such as brain, kidney and placenta. Specifically, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, but is downregulated in adult rat brain with the exception of the choroid plexus, where SMIT expression remains high. In kidney, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD). Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.
Artikel-Nr:
(BOSSBS-1945R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1945R-CY3
Lokale Artikelnummer::
BOSSBS-1945R-CY3
Beschreibung:
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
VE:
1 * 100 µl
Artikel-Nr:
(PROOMM0431.01)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0431.01
Lokale Artikelnummer::
PROOMM0431.01
Beschreibung:
Methyl-4-hydroxybenzoat Natriumsalz
VE:
1 * 500 mg
Lieferant:
Serva
Beschreibung:
Cloning Buffer, Sodium acetate buffer solution pH 5,2 (3 mol/l)
Artikel-Nr:
(MOLE25860279-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
25860279-25G
Lokale Artikelnummer::
MOLE25860279-25G
Beschreibung:
L(+)-Natriumlactat
VE:
1 * 25 g
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Artikel-Nr:
(BNUM0225-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0225-50
Lokale Artikelnummer::
BTIUBNUM0225-50
Beschreibung:
Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-3473R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3473R-HRP
Lokale Artikelnummer::
BOSSBS-3473R-HRP
Beschreibung:
WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization.WNK1 has 4 isoforms produced by alternative splicing. WNK1 is widely expressed, with highest levels observed in the testis, heart, kidney and skeletal muscle.Defects in WNK1 are a cause of pseudohypoaldosteronism type II (PHAII), an autosomal dominant disease characterized by severe hypertension, hyperkalemia, and sensitivity to thiazide diuretics which may result from a chloride shunt in the renal distal nephron.
VE:
1 * 100 µl
Artikel-Nr:
(ABCRAB104169.0025)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB104169.0025
Lokale Artikelnummer::
ABCRAB104169.0025
Beschreibung:
Natriumperfluoroctanoat
VE:
1 * 25 g
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Artikel-Nr:
(BOSSBS-13298R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13298R-A488
Lokale Artikelnummer::
BOSSBS-13298R-A488
Beschreibung:
CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher’s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12125R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12125R-A647
Lokale Artikelnummer::
BOSSBS-12125R-A647
Beschreibung:
The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT2, also designated ATA2, PRO1068 and SAT2 is encoded by the human gene SLC38A2. The functional role of SNAT2 in the nervous system is unclear. Protein expression is notably enriched in the spinal cord and brain stem nuclei of the auditory system. System A transport proteins are also present in placental tissue. These SNAT proteins may play a significant role in fetal development and inhibition of the transport system has been associated with fetal growth retardation.
VE:
1 * 100 µl
Preis auf Anfrage
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