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(5-Methylpyridin-2-yl)methanol


19 383  results were found

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Lieferant:  APOLLO SCIENTIFIC
Beschreibung:   α,α'-Dibrom-m-xylol 97+%

Lieferant:  APOLLO SCIENTIFIC
Hersteller-Artikelnummer:: BICL112-100MG
Lokale Artikelnummer:: APOSBICL112-100MG
Beschreibung:   Sulphhydryl reactive -Cleavable
VE:  1 * 100 mg

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3390R-CY3
Lokale Artikelnummer:: BOSSBS-3390R-CY3
Beschreibung:   Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis.
VE:  1 * 100 µl
Artikel-Nr: (0431-25G)

Lieferant:  VWR Chemicals
Lokale Artikelnummer:: VWRC0431-25G
Beschreibung:   pH indicator goes from yellow to blue over a range of 6.0 to 7.6. Used to trace movement of fluids from the lymph and also for demonstration of fungal hyphae within plant roots.
VE:  1 * 25 g
Artikel-Nr: (BOSSBS-3494R-CY5)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3494R-CY5
Lokale Artikelnummer:: BOSSBS-3494R-CY5
Beschreibung:   Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1.
VE:  1 * 100 µl
Lieferant:  Thermo Scientific
Beschreibung:   3,3'-Iminobis(N,N-dimethylpropylamine)
Lieferant:  Hach
Beschreibung:   Qualitative Ergebnisse mit Farbvergleich über herkömmliche Farbscheibe.
Artikel-Nr: (BLDPBD328248-1G)

Lieferant:  BLD PHARMATECH GMBH
Hersteller-Artikelnummer:: BD328248-1G
Lokale Artikelnummer:: BLDPBD328248-1G
Beschreibung:   2-Chloro-4,6-di-p-tolyl-1,3,5-triazine 95%
VE:  1 * 1 g
Lieferant:  APOLLO SCIENTIFIC
Beschreibung:   4-Bromo-1,1,1-trifluoro-2-(trifluoromethyl)butane 97%
Lieferant:  APOLLO SCIENTIFIC
Beschreibung:   Aphidicolin (from Nigrospora sphaerica)
Lieferant:  Thermo Scientific
Beschreibung:   m-Kresolpurpur, rein Indikator-Qualität
Lieferant:  Alfa Aesar
Beschreibung:   DSG (Disuccinimidyl glutarate) 97%
Artikel-Nr: (APOSOR920918-5G)

Lieferant:  APOLLO SCIENTIFIC
Hersteller-Artikelnummer:: OR920918-5G
Lokale Artikelnummer:: APOSOR920918-5G
Beschreibung:   4,4'-(1,2-Ethandiyl)dipyridin 95%
VE:  1 * 5 g
Lieferant:  VWR Chemicals
Beschreibung:   Ammoniumeisen(III)sulfat Dodecahydrat 98,5-102% ACS

Lieferant:  APOLLO SCIENTIFIC
Hersteller-Artikelnummer:: PC0451-25G
Lokale Artikelnummer:: APOSPC0451-25G
Beschreibung:   Chlor(di-1-pyrrolidinyl)methyliumhexafluorophosphat
VE:  1 * 25 g
Lieferant:  Thermo Scientific
Beschreibung:   Acridinorange (Zinkchlorid-Doppelsalz) ∼55% (Farbstoffgehalt), rein
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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