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Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Human IFN-γ is not cross-reactive with mouse IFN-γ.
Artikel-Nr:
(PRSI90-319)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-319
Lokale Artikelnummer::
PRSI90-319
Beschreibung:
Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognises beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognises alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-601)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-601
Lokale Artikelnummer::
PRSI91-601
Beschreibung:
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. CADM1 may contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, it may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. The protein acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly. It may be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. CADM1 may play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Human IFN-γ is not cross-reactive with mouse IFN-γ.
Artikel-Nr:
(PRSI76-242)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-242
Lokale Artikelnummer::
PRSI76-242
Beschreibung:
The OKT3 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
VE:
1 * 0,1 mg
Lieferant:
Serva
Beschreibung:
L(-)-Glutathion (reduzierte Form)
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
L(-)-Glutathion (reduzierte Form), Millipore®
Artikel-Nr:
(0230-07)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR0230-07
Beschreibung:
Crystals. Lot analysis on label.
VE:
1 * 12 kg
Lieferant:
MICRONOVA
Beschreibung:
Reinigen Sie Streifenvorhänge aus Vinyl einfach und effizient mit einem einfachen, „gegabelten“ Rahmen, der den Vorhang oben greift und nach unten gleitet, wodurch beide Seiten gleichzeitig effektiv gereinigt werden. Entwickelt für den Einsatz in Reinräumen. Gammasterilisierte Bezüge für aseptische Umgebungen.
Artikel-Nr:
(PRSI96-419)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-419
Lokale Artikelnummer::
PRSI96-419
Beschreibung:
Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3).
VE:
1 * 200 µG
Artikel-Nr:
(PRSI96-416)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-416
Lokale Artikelnummer::
PRSI96-416
Beschreibung:
Immunoglobulin G3 (IgG3) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-3 chain C region (IgG3-Fc / IGHG3) contains two constant regions of IgG3 H chain (CH2, CH3).
VE:
1 * 200 µG
Artikel-Nr:
(PRSI90-017)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-017
Lokale Artikelnummer::
PRSI90-017
Beschreibung:
IDO catalyses the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumours, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-823)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-823
Lokale Artikelnummer::
PRSI91-823
Beschreibung:
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. XCL1 plays a role in inflammatory and immunological responses, inducing leukocyte migration and activation. XCL1 induces chemotactic function by binding to a chemokine receptor called XCR1. XCL1 is closely related to another chemokine called XCL2.
VE:
1 * 50 µG
Lieferant:
Thermo Scientific
Beschreibung:
Tetrahydro-4H-pyran-4-on
Artikel-Nr:
(PRSI92-615)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-615
Lokale Artikelnummer::
PRSI92-615
Beschreibung:
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFN-ƴ), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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