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4,6-Dihydroxy-5-methylpyrimidine
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4,6-Dihydroxy-5-methylpyrimidine
Artikel-Nr:
(BOSSBS-7525R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7525R-CY5.5
Lokale Artikelnummer::
BOSSBS-7525R-CY5.5
Beschreibung:
This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3430R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3430R-A680
Lokale Artikelnummer::
BOSSBS-3430R-A680
Beschreibung:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3430R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3430R-A750
Lokale Artikelnummer::
BOSSBS-3430R-A750
Beschreibung:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9504R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9504R-CY7
Lokale Artikelnummer::
BOSSBS-9504R-CY7
Beschreibung:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6867R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6867R-A555
Lokale Artikelnummer::
BOSSBS-6867R-A555
Beschreibung:
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10042R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10042R-A555
Lokale Artikelnummer::
BOSSBS-10042R-A555
Beschreibung:
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7688R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7688R-CY7
Lokale Artikelnummer::
BOSSBS-7688R-CY7
Beschreibung:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7688R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7688R-CY3
Lokale Artikelnummer::
BOSSBS-7688R-CY3
Beschreibung:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7688R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7688R-CY5
Lokale Artikelnummer::
BOSSBS-7688R-CY5
Beschreibung:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(PRSI92-447)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-447
Lokale Artikelnummer::
PRSI92-447
Beschreibung:
Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best characterised for their roles in immune regulation, fertility, thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signalling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues, including the central nervous, reproductive, immune, and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.
VE:
1 * 50 µG
Lieferant:
Thermo Fisher Scientific
Beschreibung:
RevertAid™ H Minus First Strand cDNA Synthesis Kit is a complete system for efficient synthesis of first strand cDNA from RNA templates. The kit includes RevertAid™ H Minus Reverse Transcriptase, which has a point mutation that completely eliminates RNase H activity. Therefore, it does not degrade RNA in RNA-DNA hybrids during synthesis of the first strand cDNA.
Artikel-Nr:
(141-1449)
Lieferant:
Diversey
Hersteller-Artikelnummer::
7514852
Lokale Artikelnummer::
DIVY7514852
Beschreibung:
ClearKlens Bi-Spore ist ein schnell wirksames, stabiles Zwei-Komponenten-System zur Erzeugung von Chlordioxid, das entwickelt wurde, um die sterilen Produktionsanlagen in der Pharmaindustrie zu desinfizieren. Wirkt gemäß dem europäischen Sporizidtest (CEN 13704) bereits nach 5 Minuten Einwirkzeit, innerhalb von 5 - 8 Minuten nach Oberflächenkontakt.
VE:
1 * 25 SET
Artikel-Nr:
(PRSI96-647)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-647
Lokale Artikelnummer::
PRSI96-647
Beschreibung:
Renin is also known as REN and angiotensinogenase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS), and plays an essential role in the elevation of arterial blood pressure and increased sodium retention by the kidney. Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. Renin is secreted from kidney cells, which are activated via signaling from the macula densa, which responds to the rate of fluid flow through the distal tubule, by decreases in renal perfusion pressure (through stretch receptors in the vascular wall), and by sympathetic nervous stimulation, mainly through beta-1 receptor activation. Renin can bind to ATP6AP2, which results in a fourfold increase in the conversion of angiotensinogen to angiotensin I over that shown by soluble renin. In addition, renin binding results in phosphorylation of serine and tyrosine residues of ATP6AP2. The level of renin mRNA appears to be modulated by the binding of HADHB, HuR and CP1 to a regulatory region in the 3' UTR. An over-active renin-angiotension system leads to vasoconstriction and retention of sodium and water. These effects lead to hypertension. Therefore, renin inhibitors can be used for the treatment of hypertension.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-7688R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7688R-FITC
Lokale Artikelnummer::
BOSSBS-7688R-FITC
Beschreibung:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10042R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10042R-CY7
Lokale Artikelnummer::
BOSSBS-10042R-CY7
Beschreibung:
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9504R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9504R-CY5.5
Lokale Artikelnummer::
BOSSBS-9504R-CY5.5
Beschreibung:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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