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5-Fluoro-4-iodopyridin-2(1H)-one
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5-Fluoro-4-iodopyridin-2(1H)-one
Artikel-Nr:
(BOSSBS-1498R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1498R-A680
Lokale Artikelnummer::
BOSSBS-1498R-A680
Beschreibung:
Fatty acid synthetase catalyses the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1070R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1070R-A750
Lokale Artikelnummer::
BOSSBS-1070R-A750
Beschreibung:
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11347R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11347R-A750
Lokale Artikelnummer::
BOSSBS-11347R-A750
Beschreibung:
Postsynaptic scaffolding protein at the parallel fiber-Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton and various Signalling molecules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7054R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7054R-CY3
Lokale Artikelnummer::
BOSSBS-7054R-CY3
Beschreibung:
Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.Tissue specificity: Ubiquitous. Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6419R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6419R-CY5.5
Lokale Artikelnummer::
BOSSBS-6419R-CY5.5
Beschreibung:
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15364R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15364R-CY5
Lokale Artikelnummer::
BOSSBS-15364R-CY5
Beschreibung:
GPR85.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12915R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12915R-FITC
Lokale Artikelnummer::
BOSSBS-12915R-FITC
Beschreibung:
c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8444R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8444R-A680
Lokale Artikelnummer::
BOSSBS-8444R-A680
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localisation and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0011R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0011R-A350
Lokale Artikelnummer::
BOSSBS-0011R-A350
Beschreibung:
GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7747R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7747R-CY5.5
Lokale Artikelnummer::
BOSSBS-7747R-CY5.5
Beschreibung:
DCTN6 belongs to the pointed end complex of the dynactin shoulder complex tpgether with the DCTN4, DCTN5 and DCTN6 subunits and ACTR10. DCTN6 contains an RGD (Arg-Gly-Asp) motif in the N terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. The exact function of this gene is not known.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6520R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6520R-A680
Lokale Artikelnummer::
BOSSBS-6520R-A680
Beschreibung:
High-affinity epithelial cell surface receptor for APF. Mediates the anchoring of the endoplasmic reticulum to microtubules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3376R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3376R-CY5.5
Lokale Artikelnummer::
BOSSBS-3376R-CY5.5
Beschreibung:
The Raf family of serine/threonine specific kinases is comprised of three members (aRaf, bRaf, and cRaf) that play a critical role in regulating cell growth and differentiation, and couple growth factor receptor stimulation to nuclear transcription factors via the Ras/mitogen activated protein kinase (MAPK) pathway. cRaf kinase (also known as Raf1) is a small GTPase like kinase of 73 kDa, and is a signal transducer of multiple extracellular stimuli that is regulated by several pathways, and that once activated, phosphorylates MEK which in turn phosphorylates ERK. Raf1 is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is part of the Ras dependent signaling pathway from receptors to the nucleus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9082R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9082R-A488
Lokale Artikelnummer::
BOSSBS-9082R-A488
Beschreibung:
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13314R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13314R-CY7
Lokale Artikelnummer::
BOSSBS-13314R-CY7
Beschreibung:
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6854R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6854R-A680
Lokale Artikelnummer::
BOSSBS-6854R-A680
Beschreibung:
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13621R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13621R-A680
Lokale Artikelnummer::
BOSSBS-13621R-A680
Beschreibung:
The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A (C-type lectin domain family 9 member A), also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin-like receptor (CTLR) that acts as an activation receptor. The gene encoding CLEC-9A maps to human chromosome 12p13.2 and mouse chromosome 6 F3.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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