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BIOSS INC
Artikel-Nr:
(663-2101)
Lieferant:
KNICK
Hersteller-Artikelnummer::
703
Lokale Artikelnummer::
KNIC703
Beschreibung:
This bench top meter can be operated with either 2-electrode or 4-electrode sensors. In conjunction with the Knick ZU 6985 4-electrode sensor, the meter functions reliably over a wide conductivity range from <1,00 to >1000 mS/cm.
VE:
1 * 1 ST
Artikel-Nr:
(TCIAI0747-100MG)
Lieferant:
TCI
Hersteller-Artikelnummer::
I0747-100MG
Lokale Artikelnummer::
TCIAI0747-100MG
Beschreibung:
Imiquimod ≥98,0% (durch HPLC, titrimetrische Analyse)
VE:
1 * 100 mg
Artikel-Nr:
(BLEG409502)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
409502
Lokale Artikelnummer::
BLEG409502
Beschreibung:
Anti-Ig light chain κ Rat Monoclonal Antibody [clone: RMK-45]
VE:
1 * 500 µG
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(NEUB0725-80-45)
Lieferant:
NEUBERT VOLUME GLASSWAERE
Hersteller-Artikelnummer::
0725-80-45
Lokale Artikelnummer::
NEUB0725-80-45
Beschreibung:
The cooling traps are made from borosilicate glass 3.3, with core at the bottom, two 10 mm glass poles and ground clamp made of PE.
VE:
1 * 1 ST
Artikel-Nr:
(OHAU30770938)
Lieferant:
OHAUS
Hersteller-Artikelnummer::
30770938
Lokale Artikelnummer::
OHAU30770938
Beschreibung:
Universal platform, 30×22 cm
VE:
1 * 1 ST
Lieferant:
GLASWARENFABRIK KARL HECHT
Beschreibung:
Borosilikatglas, braun, beschichtet.
Artikel-Nr:
(BOSSBS-4281R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4281R-A647
Lokale Artikelnummer::
BOSSBS-4281R-A647
Beschreibung:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4281R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4281R-HRP
Lokale Artikelnummer::
BOSSBS-4281R-HRP
Beschreibung:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
VE:
1 * 100 µl
Artikel-Nr:
(EHERXA11530000AL)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
XA11530000AL
Lokale Artikelnummer::
EHERXA11530000AL
Beschreibung:
Organic Standard, Chlorotoluron (3-(3-Chloro-p-tolyl)-1,1-dimethylurea) 100 µg/ml in acetonitrile, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(EHERL11530000AL)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
L11530000AL
Lokale Artikelnummer::
EHERL11530000AL
Beschreibung:
Organic Standard, Chlortoluron (3-(3-Chlor-p-tolyl)-1,1-dimethylharnstoff) 10 µg/ml in Acetonitril, Packung: Glasflasche
VE:
1 * 10 mL
Lieferant:
Alfa Aesar
Beschreibung:
Telmisartan 99%
Artikel-Nr:
(BOSSBS-13587R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13587R-A488
Lokale Artikelnummer::
BOSSBS-13587R-A488
Beschreibung:
Nolz 1 is a 646 amino acid nuclear protein that is thought to function as a transcriptional repressor and is highly expressed in developing striatum. Additionally, Nolz-1 has been suggested to play a role in neural differentiation. A member of the Elbow/Noc family, Nolz-1 exists as three alternatively spliced isoforms and contains one C2H2-type zinc finger. The gene encoding Nolz-1 maps to human chromosome 10, which makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11945R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11945R-HRP
Lokale Artikelnummer::
BOSSBS-11945R-HRP
Beschreibung:
Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9948R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9948R-A680
Lokale Artikelnummer::
BOSSBS-9948R-A680
Beschreibung:
Encoding over 1100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf42 gene product has been provisionally designated C12orf42 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10056R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10056R-CY5
Lokale Artikelnummer::
BOSSBS-10056R-CY5
Beschreibung:
KNDC1 is a 1,749 amino acid protein that contains two KIND domains and an N-terminal Ras-GEF domain. Expressed in the cerebral cortex, KNDC1 is a likely guanine nucleotide exchange factor (GEF). Existing as six alternatively spliced isoforms, the gene encoding KNDC1 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8229R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8229R-A350
Lokale Artikelnummer::
BOSSBS-8229R-A350
Beschreibung:
Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM101A gene product has been provisionally designated FAM101A pending further characterization.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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