Methyl+3-amino-7-fluorobenzo[b]thiophene-2-carboxylate
Artikel-Nr:
(BOSSBS-1165R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1165R-A680
Lokale Artikelnummer::
BOSSBS-1165R-A680
Beschreibung:
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalisation. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7665R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7665R
Lokale Artikelnummer::
BOSSBS-7665R
Beschreibung:
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7665R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7665R-CY7
Lokale Artikelnummer::
BOSSBS-7665R-CY7
Beschreibung:
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0074R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0074R-A680
Lokale Artikelnummer::
BOSSBS-0074R-A680
Beschreibung:
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P1, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
VE:
1 * 100 µl
Artikel-Nr:
(USBI042624-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042624-FITC
Lokale Artikelnummer::
USBI042624-FITC
Beschreibung:
Anti-TBB8B Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-2514R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2514R-CY5.5
Lokale Artikelnummer::
BOSSBS-2514R-CY5.5
Beschreibung:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0356R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0356R-FITC
Lokale Artikelnummer::
BOSSBS-0356R-FITC
Beschreibung:
Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0356R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0356R-CY7
Lokale Artikelnummer::
BOSSBS-0356R-CY7
Beschreibung:
Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0356R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0356R-HRP
Lokale Artikelnummer::
BOSSBS-0356R-HRP
Beschreibung:
Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0356R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0356R-A555
Lokale Artikelnummer::
BOSSBS-0356R-A555
Beschreibung:
Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2514R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2514R-A647
Lokale Artikelnummer::
BOSSBS-2514R-A647
Beschreibung:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2514R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2514R-A488
Lokale Artikelnummer::
BOSSBS-2514R-A488
Beschreibung:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6183R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6183R-A680
Lokale Artikelnummer::
BOSSBS-6183R-A680
Beschreibung:
Reg protein is stimulated during the regeneration of pancreatic islets. In human, there are four REG family genes; REG 1 alpha, REG 1 beta, REG-related sequence (RS) and HIP/PAP. These Reg-related proteins are classified into four subfamilies according to their amino-acid sequences, but they share a similar structure and physiological function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6183R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6183R-A350
Lokale Artikelnummer::
BOSSBS-6183R-A350
Beschreibung:
Reg protein is stimulated during the regeneration of pancreatic islets. In human, there are four REG family genes; REG 1 alpha, REG 1 beta, REG-related sequence (RS) and HIP/PAP. These Reg-related proteins are classified into four subfamilies according to their amino-acid sequences, but they share a similar structure and physiological function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0920R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0920R-A555
Lokale Artikelnummer::
BOSSBS-0920R-A555
Beschreibung:
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4995R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4995R-A680
Lokale Artikelnummer::
BOSSBS-4995R-A680
Beschreibung:
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Preis auf Anfrage
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