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cis-4-Decenal


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Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3541R-A750
Lokale Artikelnummer:: BOSSBS-3541R-A750
Beschreibung:   Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically Recognises phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
VE:  1 * 100 µl
Lieferant:  FLUOROCHEM
Beschreibung:   Perfluordecahydronaphthalin (Gemisch der cis- und trans-Isomeren)
Lieferant:  SIGMA ALDRICH MICROSCOPY
Beschreibung:   Alcian Blue solution has been used in the histological staining of acidic glycosaminoglycans (GAGs; mucopolysaccharides) that are carboxylated or sulfated. Sulfated glycosaminoglycans appear to be the preferred substrate for alcian blue at pH 2.5. Alcian blue has been used to stain hyaluronan (HA), a nonsulfated GAG, but the intensity of the staining of HA is affected by the method of tissue fixation used. Alcian blue staining of GAGs in tissue may be modified through the addition of an electrolyte such as magnesium chloride.
Lieferant:  Sigma-Aldrich
Beschreibung:   1-Methoxy-1,3-butadien (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
Lieferant:  Thermo Scientific
Beschreibung:   Methylenblau Trihydrat, rein, zertifiziert residual water

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11270R-A647
Lokale Artikelnummer:: BOSSBS-11270R-A647
Beschreibung:   HSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. It can serve as a co-chaperone for steroid hormone nuclear receptors to govern appropriate hormone action in target tissues. The protein can associate with phytanoyl-CoA alpha-hydroxylase (PHYH) and with HSP90 through a series of tetratricopeptide repeat (TPR) domains. HSP 56 is a TRPC ion channel accessory protein that modulates channel activation following receptor stimulation.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11270R-A350
Lokale Artikelnummer:: BOSSBS-11270R-A350
Beschreibung:   HSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. It can serve as a co-chaperone for steroid hormone nuclear receptors to govern appropriate hormone action in target tissues. The protein can associate with phytanoyl-CoA alpha-hydroxylase (PHYH) and with HSP90 through a series of tetratricopeptide repeat (TPR) domains. HSP 56 is a TRPC ion channel accessory protein that modulates channel activation following receptor stimulation.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-5845R-CY5
Lokale Artikelnummer:: BOSSBS-5845R-CY5
Beschreibung:   Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-5845R-CY7
Lokale Artikelnummer:: BOSSBS-5845R-CY7
Beschreibung:   Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-5845R-A750
Lokale Artikelnummer:: BOSSBS-5845R-A750
Beschreibung:   Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localised to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localised to the FNIII domain.
VE:  1 * 100 µl
Artikel-Nr: (J61666.ME)

Lieferant:  Alfa Aesar
Hersteller-Artikelnummer:: J61666.ME
Lokale Artikelnummer:: ALFAJ61666.ME
Beschreibung:   13-cis-Retinoic acid
VE:  1 * 500 mg

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-5845R-A488
Lokale Artikelnummer:: BOSSBS-5845R-A488
Beschreibung:   Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
VE:  1 * 100 µl
Lieferant:  Alfa Aesar
Beschreibung:   Hämatoxylin Hydrat, (max. 6% H₂O)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-8687R-A680
Lokale Artikelnummer:: BOSSBS-8687R-A680
Beschreibung:   p53, a DNA-binding, oligomerisation domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localises to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-8333R-A555
Lokale Artikelnummer:: BOSSBS-8333R-A555
Beschreibung:   RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:  1 * 100 µl
Lieferant:  FLUOROCHEM
Beschreibung:   4-Aminocyclohexancarbonsäure (Gemisch der cis- und trans-Isomeren)
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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