5-Chloro-1,6-naphthyridine
Artikel-Nr:
(USBI127470)
Lieferant:
US Biological
Hersteller-Artikelnummer::
127470
Lokale Artikelnummer::
USBI127470
Beschreibung:
Anti-GOSR1 Mouse Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-11270R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11270R-A555
Lokale Artikelnummer::
BOSSBS-11270R-A555
Beschreibung:
HSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. It can serve as a co-chaperone for steroid hormone nuclear receptors to govern appropriate hormone action in target tissues. The protein can associate with phytanoyl-CoA alpha-hydroxylase (PHYH) and with HSP90 through a series of tetratricopeptide repeat (TPR) domains. HSP 56 is a TRPC ion channel accessory protein that modulates channel activation following receptor stimulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11270R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11270R-FITC
Lokale Artikelnummer::
BOSSBS-11270R-FITC
Beschreibung:
HSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. It can serve as a co-chaperone for steroid hormone nuclear receptors to govern appropriate hormone action in target tissues. The protein can associate with phytanoyl-CoA alpha-hydroxylase (PHYH) and with HSP90 through a series of tetratricopeptide repeat (TPR) domains. HSP 56 is a TRPC ion channel accessory protein that modulates channel activation following receptor stimulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3541R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3541R-CY3
Lokale Artikelnummer::
BOSSBS-3541R-CY3
Beschreibung:
Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5845R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5845R-A350
Lokale Artikelnummer::
BOSSBS-5845R-A350
Beschreibung:
Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12542R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12542R-HRP
Lokale Artikelnummer::
BOSSBS-12542R-HRP
Beschreibung:
Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB3 and Luman), CREM-1, CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-5 (ATFx), which can localize to the cytoplasm or the nucleus, binds DNA as a dimer. It interacts with CCND3 and PTP4A1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12287R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12287R-CY5
Lokale Artikelnummer::
BOSSBS-12287R-CY5
Beschreibung:
Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules; and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3541R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3541R-A350
Lokale Artikelnummer::
BOSSBS-3541R-A350
Beschreibung:
Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Methylenblau Hydrat 96+%, hochrein biologische Färbemittel
Artikel-Nr:
(BOSSBS-12287R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12287R-FITC
Lokale Artikelnummer::
BOSSBS-12287R-FITC
Beschreibung:
Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules; and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8333R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-A750
Lokale Artikelnummer::
BOSSBS-8333R-A750
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localises on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognises retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8333R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-HRP
Lokale Artikelnummer::
BOSSBS-8333R-HRP
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Artikel-Nr:
(EHERC15990000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C15990000
Lokale Artikelnummer::
EHERC15990000
Beschreibung:
Permethrin (Gemisch der cis- und trans-Isomeren)
VE:
1 * 0,25 g
Artikel-Nr:
(CHMPFL13614.POR)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL13614.POR
Lokale Artikelnummer::
CHMPFL13614.POR
Beschreibung:
6-Iod-2,4,5-trichlorphenol
VE:
1 * 1 ST
Lieferant:
ELTEN
Beschreibung:
ESD-Sicherheitsschuh aus hydrophobiertem Mikrofaser/hydrophobiertem Cordura®-Textil-Obermaterial und einer Sohle aus PU/PU (Ergo-Active 2). Typ 3: Für schmale Füße mit mittlerer Zehenlänge, schmaler Ballen- und Fersenbreite, mittlerem Ballenwinkel.
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Lieferant:
Sigma-Aldrich
Beschreibung:
Phytol (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
Preis auf Anfrage
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