Methyl-2-chloro-2-cyclopropylideneacetate
Artikel-Nr:
(BOSSBS-13046R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13046R-A750
Lokale Artikelnummer::
BOSSBS-13046R-A750
Beschreibung:
Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4176R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4176R-A680
Lokale Artikelnummer::
BOSSBS-4176R-A680
Beschreibung:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Dichlormethan ≥99,7% stabilisiert für die Spektrophotometrie
Lieferant:
Lovibond Tintometer
Beschreibung:
MINIKIT provides quick and simple tests for the analysis of boiler water, cooling water, drinking and industrial water.
Artikel-Nr:
(PRSI28-234)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-234
Lokale Artikelnummer::
PRSI28-234
Beschreibung:
Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
VE:
1 * 100 µG
Lieferant:
PERKIN ELMER GC INSTRUMENTS
Beschreibung:
Halb-demontierbare Natriumchlorid(NaCl)-Zellfenster, ein Paar, Stärke: 4 mm
Artikel-Nr:
(BOSSBS-1935R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1935R-CY3
Lokale Artikelnummer::
BOSSBS-1935R-CY3
Beschreibung:
Uteroglobin belongs to the family of secretoglobins and is a secreted protein product of nonciliated bronchiolar Clara cells. There is convincing data suggesting it has phospholipase A2 inhibitory activity, as well as, a number of other immunomodulatory features including inhibition of interferon gamma signalling and Th1 vs. Th2 lymphocyte regulation. It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction. Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994. In serum, its increase is associated with age, asbestos, nitrogen chloride and ozone exposure, sarcoidosis and high PEEP ventilation. Decreased serum CC16 levels are found after pulmonary resection, in silica-exposed workers, smokers and in asthma. Decreased CC16 concentrations were also found in the amniotic fluid of fetuses suffering from pulmonary hypoplasia caused by various mechanisms (diaphragmatic hernia, diabetic fetopathy, Turner and Down syndrome). In pleural effusions, the CC16 concentration appears to be associated with its diffusion from the lung as evidenced by high CC16 levels in cardiac pleural congestion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1935R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1935R-CY7
Lokale Artikelnummer::
BOSSBS-1935R-CY7
Beschreibung:
Uteroglobin belongs to the family of secretoglobins and is a secreted protein product of nonciliated bronchiolar Clara cells. There is convincing data suggesting it has phospholipase A2 inhibitory activity, as well as, a number of other immunomodulatory features including inhibition of interferon gamma signalling and Th1 vs. Th2 lymphocyte regulation. It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction. Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994. In serum, its increase is associated with age, asbestos, nitrogen chloride and ozone exposure, sarcoidosis and high PEEP ventilation. Decreased serum CC16 levels are found after pulmonary resection, in silica-exposed workers, smokers and in asthma. Decreased CC16 concentrations were also found in the amniotic fluid of fetuses suffering from pulmonary hypoplasia caused by various mechanisms (diaphragmatic hernia, diabetic fetopathy, Turner and Down syndrome). In pleural effusions, the CC16 concentration appears to be associated with its diffusion from the lung as evidenced by high CC16 levels in cardiac pleural congestion.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Dichlormethan 99.8% stabilisiert für die HPLC
Artikel-Nr:
(PIER34035)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
34035
Lokale Artikelnummer::
PIER34035
Beschreibung:
NBT (nitro-blue tetrazolium chloride) yields a blue-purple, water-insoluble product upon reduction of the tetrazolium salt. The product of reduction is NBT-formazan. This substrate is widely used for immunochemistry applications because the color is linear and stable. NBT is used as the substrate for both glucose oxidase and alkaline phosphatase systems.
VE:
1 * 1 g
Lieferant:
Thermo Scientific
Beschreibung:
Nicotinamidin Hydrochlorid
Artikel-Nr:
(FLUO018620-10G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
018620-10G
Lokale Artikelnummer::
FLUO018620-10G
Beschreibung:
4-Chlormethyl-o-xylol
VE:
1 * 10 g
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Lieferant:
BIONET RESEARCH
Beschreibung:
O-[(2,5-Dichlorophenyl)methyl]hydroxylamine hydrochloride
Artikel-Nr:
(PROOMM0049.00)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0049.00
Lokale Artikelnummer::
PROOMM0049.00
Beschreibung:
Thiamin Hydrochlorid
VE:
1 * 500 mg
Lieferant:
Thermo Scientific
Beschreibung:
Tetrachlorgold(III)säure Trihydrat ACS
Artikel-Nr:
(BOSSBS-13046R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13046R-A647
Lokale Artikelnummer::
BOSSBS-13046R-A647
Beschreibung:
Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
VE:
1 * 100 µl
Preis auf Anfrage
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