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BIOSS INC
Artikel-Nr:
(BOSSBS-13276R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13276R-A680
Lokale Artikelnummer::
BOSSBS-13276R-A680
Beschreibung:
Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into alpha, beta, and gamma families, and the beta and gamma-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. gamma-crystallins are structural proteins in the lens, and they exists as monomers which typically lack connecting peptides and terminal extensions. The gamma-crystallins include seven closely related gamma A, gamma B, gamma C, gamma D, gamma E, gamma F, and gamma G-crystallin, as well as the gamma N and gamma S-crystallin genes. The gamma-crystallins are differentially regulated after early development, and are involved in cataract formation as a result of either age-related protein degradation or genetic mutation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0442R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0442R-A555
Lokale Artikelnummer::
BOSSBS-0442R-A555
Beschreibung:
ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1976R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1976R-CY5
Lokale Artikelnummer::
BOSSBS-1976R-CY5
Beschreibung:
Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6938R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6938R-CY5
Lokale Artikelnummer::
BOSSBS-6938R-CY5
Beschreibung:
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11950R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11950R-HRP
Lokale Artikelnummer::
BOSSBS-11950R-HRP
Beschreibung:
Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5013R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5013R-CY7
Lokale Artikelnummer::
BOSSBS-5013R-CY7
Beschreibung:
Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11805R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11805R-CY7
Lokale Artikelnummer::
BOSSBS-11805R-CY7
Beschreibung:
AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1–3). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4246R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4246R-A680
Lokale Artikelnummer::
BOSSBS-4246R-A680
Beschreibung:
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9289R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9289R-A680
Lokale Artikelnummer::
BOSSBS-9289R-A680
Beschreibung:
The deduced 257 amino acid protein PACRG (Parkin co-regulated gene) shows potential links to the ubiquitin/proteasome system. PACRG and Parkin are attached in a head-to-head arrangement on opposite DNA strands and share a common 5' flanking promoter region. The PACRG gene maps to chromosome 6q26; Northern blot analysis detects PACRG expression in all tissues examined except placenta. Using a positional cloning strategy in 197 Vietnamese leprosy simplex families (i.e. families with two unaffected parents and one affected child), significant connections between leprosy and 17 markers in the 5' regulatory region that PARK2 and PACRG share were observed. Possession of two or more of the 17 risk alleles is highly predictive of leprosy.PACRG is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9349R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9349R-A647
Lokale Artikelnummer::
BOSSBS-9349R-A647
Beschreibung:
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12478R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12478R-A350
Lokale Artikelnummer::
BOSSBS-12478R-A350
Beschreibung:
The Annexins constitute a family of structurally-related, relatively abundant proteins that exhibit Ca2+-dependent binding to phospholipids. Annexins function in multiple aspects of cell biology including regulation of membrane trafficking, transmembrane channel activity, inhibition of phospholipase A2, inhibition of coagulation and mediation of cell-matrix interactions. Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Two alternative splicing isoforms of Annexin A13 exist, both of which bind to rafts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12478R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12478R-CY3
Lokale Artikelnummer::
BOSSBS-12478R-CY3
Beschreibung:
The Annexins constitute a family of structurally-related, relatively abundant proteins that exhibit Ca2+-dependent binding to phospholipids. Annexins function in multiple aspects of cell biology including regulation of membrane trafficking, transmembrane channel activity, inhibition of phospholipase A2, inhibition of coagulation and mediation of cell-matrix interactions. Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Two alternative splicing isoforms of Annexin A13 exist, both of which bind to rafts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12520R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12520R-FITC
Lokale Artikelnummer::
BOSSBS-12520R-FITC
Beschreibung:
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0699R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0699R-A680
Lokale Artikelnummer::
BOSSBS-0699R-A680
Beschreibung:
Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6221R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6221R-HRP
Lokale Artikelnummer::
BOSSBS-6221R-HRP
Beschreibung:
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6775R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6775R-FITC
Lokale Artikelnummer::
BOSSBS-6775R-FITC
Beschreibung:
FASTKD2 belongs to the FAST kinase family and it contains 1 RAP domain. There are two isoforms.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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